Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RABGGTB | P53611 | 2/20 | 0.33 |
| ▸ | RABGGTA | Q92696 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7275840 | 0.92 | KDM5A (0.36) | RABGGTBRABGGTASPHK1CTSSCTSK | |
| SCHEMBL9444999 | 0.89 | EPHX1 (0.33) | RABGGTBRABGGTASMN1; SMN2SPHK1CTSS | |
| SCHEMBL9444993 | 0.89 | EPHX1 (0.33) | RABGGTBRABGGTASMN1; SMN2SPHK1CTSS | |
| SCHEMBL9438130 | 0.88 | SPHK1 (0.32) | RABGGTBRABGGTASPHK1CTSSCTSK | |
| SCHEMBL7378719 | 0.88 | SPHK1 (0.32) | RABGGTBRABGGTASPHK1CTSSCTSK | |
| SCHEMBL7378718 | 0.88 | SPHK1 (0.32) | RABGGTBRABGGTASPHK1CTSSCTSK | |
| SCHEMBL7387129 | 0.87 | RABGGTB (0.33) | RABGGTBRABGGTA | |
| SCHEMBL9516511 | 0.85 | EPHX1 (0.33) | RABGGTBRABGGTASMN1; SMN2SPHK1CTSS | |
| SCHEMBL7300252 | 0.85 | EPHX1 (0.33) | RABGGTBRABGGTASMN1; SMN2SPHK1CTSS | |
| SCHEMBL7372551 | 0.85 | EPHX1 (0.33) | RABGGTBRABGGTASMN1; SMN2SPHK1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0386611-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1990-09-12 | — | — | EP | disclosed |