Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 3/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RABGGTB | P53611 | 2/20 | 0.31 |
| ▸ | RABGGTA | Q92696 | 2/20 | 0.31 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10448591 | 0.92 | RABGGTB (0.33) | SPHK1LMNARABGGTBRABGGTAEPHX1 | |
| SCHEMBL9444999 | 0.85 | EPHX1 (0.33) | SPHK1RABGGTBRABGGTAEPHX1CTSD | |
| SCHEMBL9444993 | 0.85 | EPHX1 (0.33) | SPHK1RABGGTBRABGGTAEPHX1CTSD | |
| SCHEMBL9438130 | 0.84 | SPHK1 (0.32) | SPHK1RABGGTBRABGGTAEPHX1CTSD | |
| SCHEMBL7378718 | 0.84 | SPHK1 (0.32) | SPHK1RABGGTBRABGGTAEPHX1CTSD | |
| SCHEMBL7378719 | 0.84 | SPHK1 (0.32) | SPHK1RABGGTBRABGGTAEPHX1CTSD | |
| SCHEMBL7387129 | 0.83 | RABGGTB (0.33) | RABGGTBRABGGTA | |
| SCHEMBL7300252 | 0.82 | EPHX1 (0.33) | SPHK1RABGGTBRABGGTAEPHX1CTSD | |
| SCHEMBL9516511 | 0.82 | EPHX1 (0.33) | SPHK1RABGGTBRABGGTAEPHX1CTSD | |
| SCHEMBL7267154 | 0.82 | EPHX1 (0.33) | SPHK1RABGGTBRABGGTAEPHX1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0391180-A2 | Peptide derivatives of amino acids having a renin-inhibiting effect | F. HOFFMANN-LA ROCHE AG (CH) | 1990-10-10 | — | — | EP | disclosed |