Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.50 |
| ▸ | RARB | P10826 | 3/20 | 0.48 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10345694 | 0.87 | TP53 (0.46) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL10573627 | 0.81 | TP53 (0.42) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL10973192 | 0.80 | TP53 (0.42) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL10445846 | 0.80 | NR5A1 (0.45) | TP53TSHRPLA2G4BFAAH | |
| SCHEMBL8969958 | 0.80 | FAAH (0.50) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL9842927 | 0.78 | CES2 (0.40) | — | |
| SCHEMBL10449056 | 0.77 | PPARG (0.42) | TP53TSHRLMNA | |
| SCHEMBL21224652 | 0.77 | PPARG (0.42) | TP53TSHRLMNA | |
| SCHEMBL7845911 | 0.73 | NPC1 (0.72) | TP53TSHRPLA2G4BRARBNFKB1 | |
| SCHEMBL10524079 | 0.73 | NPC1 (0.72) | TP53TSHRPLA2G4BRARBNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388960-A1 | Optically active compounds and their preparation and use | HITACHI, LTD. (JP) | 1990-09-26 | — | — | EP | disclosed |