Sugi Predict

Sugi Predict / Compounds / SCHEMBL10448690

SCHEMBL10448690

SCHEMBL10448690

CCOC(=O)C(=O)C(C)(C)Br

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 6/20 0.42
▸ TRPA1 O75762 1/20 0.41
▸ LMNA P02545 3/20 0.40
▸ NPSR1 Q6W5P4 3/20 0.40
▸ HSD17B10 Q99714 1/20 0.40
▸ GLO1 Q04760 1/20 0.40
▸ MAPT P10636 4/20 0.39
▸ MEN1 O00255 3/20 0.39
▸ KMT2A Q03164 3/20 0.39
▸ S1PR4 O95977 1/20 0.39
▸ S1PR1 P21453 1/20 0.39
▸ MAPK1 P28482 1/20 0.39
▸ TSHR P16473 2/20 0.39
▸ ALOX15 P16050 1/20 0.39
▸ MGAM O43451 1/20 0.39
▸ GAA P10253 1/20 0.39
▸ SI P14410 1/20 0.39
▸ MGAM2 Q2M2H8 1/20 0.39
▸ SOAT1 P35610 1/20 0.39
▸ EGLN1 Q9GZT9 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3853357 0.80 ALDH1A1 (0.46) ALDH1A1TRPA1LMNANPSR1HSD17B10
SCHEMBL20691515 0.78 ALDH1A1 (0.43) ALDH1A1TRPA1LMNANPSR1HSD17B10
SCHEMBL20691539 0.76 ALDH1A1 (0.42) ALDH1A1TRPA1LMNANPSR1HSD17B10
SCHEMBL2133814 0.76 ALDH1A1 (0.42) ALDH1A1TRPA1LMNANPSR1HSD17B10
SCHEMBL36821 0.75 — —
SCHEMBL9746132 0.74 ALDH1A1 (0.47) ALDH1A1TRPA1LMNANPSR1HSD17B10
SCHEMBL11768714 0.74 CYP4F2 (0.41) ALDH1A1LMNANPSR1HSD17B10GLO1
SCHEMBL28438273 0.74 CYP4F2 (0.41) ALDH1A1LMNANPSR1HSD17B10GLO1
SCHEMBL247694 0.73 ALDH1A1 (0.56) ALDH1A1TRPA1LMNANPSR1HSD17B10
Methane SCHEMBL21632462 0.73 CYP4F2 (0.44) ALDH1A1TRPA1LMNAHSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12435087-B2 Modulators of DCN-1 and methods of use thereof CELLARITY, INC. (US) 2025-10-07 — — US disclosed
US-20250163058-A1 MODULATORS OF DCN-1 AND METHODS OF USE THEREOF THAMES PHARMA PARTNERS 2025-05-22 — — US disclosed
WO-2025096981-A1 MODULATORS OF DCN-1 AND METHODS OF USE THEREOF CELLARITY, INC. (US) 2025-05-08 — — WO disclosed
EP-3658590-B1 PHOTOINITIATORS FOR LIGHT-CURABLE COMPOSITIONS UNIV WIEN TECH (AT) 2024-03-27 — — EP disclosed
US-11655314-B2 Photoinitiators for light-curable compositions TECHNISCHE UNIVERSITAET WIEN (AT) 2023-05-23 — — US disclosed
US-11655314-B2 Photoinitiators for light-curable compositions TECHNISCHE UNIVERSITAET WIEN (AT) 2023-05-23 — — US disclosed
US-11655314-B2 Photoinitiators for light-curable compositions TECHNISCHE UNIVERSITAET WIEN (AT) 2023-05-23 — — US disclosed
US-11518823-B2 Photoinitiators for light-curable compositions TECHNISCHE UNIVERSITAET WIEN (AT) 2022-12-06 — — US disclosed
US-11518823-B2 Photoinitiators for light-curable compositions TECHNISCHE UNIVERSITAET WIEN (AT) 2022-12-06 — — US disclosed
US-20220235153-A1 PHOTOINITIATORS FOR LIGHT-CURABLE COMPOSITIONS TECHNISCHE UNIVERSITAET WIEN (AT) 2022-07-28 — — US disclosed
US-20220235153-A1 PHOTOINITIATORS FOR LIGHT-CURABLE COMPOSITIONS TECHNISCHE UNIVERSITAET WIEN (AT) 2022-07-28 — — US disclosed
US-20200231531-A1 PHOTOINITIATORS FOR LIGHT-CURABLE COMPOSITIONS TECHNISCHE UNIVERSITAET WIEN (AT) 2020-07-23 — — US disclosed
US-20200231531-A1 PHOTOINITIATORS FOR LIGHT-CURABLE COMPOSITIONS TECHNISCHE UNIVERSITAET WIEN (AT) 2020-07-23 — — US disclosed
EP-3658590-A1 PHOTOINITIATORS FOR LIGHT-CURABLE COMPOSITIONS Technische Universität Wien (AT) 2020-06-03 — — EP disclosed
WO-2019020805-A1 PHOTOINITIATORS FOR LIGHT-CURABLE COMPOSITIONS TECHNISCHE UNIVERSITAET WIEN (AT) 2019-01-31 — — WO disclosed
EP-0385172-A1 Process for transformation of hydroxyketo acids to hydroxyamino acids E.R. SQUIBB & SONS, INC. (US) 1990-09-05 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11655314-B2 Photoinitiators for light-curable compositions OXER1, PPOX, ORC3 ALDH1A1 901/4885TRPA1 2224/4885LMNA 1878/4885
US-11518823-B2 Photoinitiators for light-curable compositions OXER1, ORC3, PPOX ALDH1A1 874/4885TRPA1 1677/4885LMNA 2546/4885
US-20250163058-A1 MODULATORS OF DCN-1 AND METHODS OF USE THEREOF DCUN1D1, DCUN1D2, DCUN1D4 ALDH1A1 847/4885TRPA1 3341/4885LMNA 1755/4885
US-20220235153-A1 PHOTOINITIATORS FOR LIGHT-CURABLE COMPOSITIONS OXER1, PPOX, ORC3 ALDH1A1 901/4885TRPA1 2224/4885LMNA 1878/4885
US-12435087-B2 Modulators of DCN-1 and methods of use thereof DCUN1D1, DCUN1D2, DCUN1D4 ALDH1A1 847/4885TRPA1 3341/4885LMNA 1755/4885
US-20200231531-A1 PHOTOINITIATORS FOR LIGHT-CURABLE COMPOSITIONS OXER1, ORC3, PPOX ALDH1A1 874/4885TRPA1 1677/4885LMNA 2546/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.