SCHEMBL1045003

SCHEMBL1045003

[CH2]COc1c(Br)cc(Br)cc1Br

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
CYP3A4 P08684 1/20 0.36
HSD17B10 Q99714 1/20 0.35
ALOX15 P16050 4/20 0.34
ALOX12 P18054 3/20 0.34
KLK1 P06870 1/20 0.34
THRB P10828 2/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
HRH3 Q9Y5N1 2/20 0.32
GABRA1 P14867 1/20 0.32
GABRB1 P18505 1/20 0.32
GABRA2 P47869 1/20 0.32
GABRB2 P47870 1/20 0.32
ALDH1A1 P00352 2/20 0.32
AKR1B1 P15121 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7077771 0.81 KLK1 (0.40) TSHRTDP1CYP3A4HSD17B10ALOX15
SCHEMBL10507317 0.81 NMT1 (0.34) MAPTHPGDKMT2AMEN1ALDH1A1
SCHEMBL6280188 0.81 KMT2A (0.38) TSHRKLK1THRBMAPTKMT2A
SCHEMBL28891144 0.80 GABRA1 (0.42) TSHRHSD17B10ALOX15ALOX12THRB
SCHEMBL11451272 0.79 TSHR (0.39) TSHRTDP1CYP3A4HSD17B10ALOX15
SCHEMBL94118 0.79 KLK1 (0.45) TSHRTDP1CYP3A4HSD17B10ALOX15
SCHEMBL9066305 0.79 MEN1 (0.35) TDP1ALOX15GAAMAPTHPGD
SCHEMBL9066379 0.79 ALOX15 (0.37) TSHRTDP1ALOX15GAAMAPT
SCHEMBL9241719 0.77 KLK1 (0.48) TSHRTDP1CYP3A4KLK1THRB
SCHEMBL9240974 0.77 KLK1 (0.53) TSHRTDP1CYP3A4KLK1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 467 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116003693-A Holographic photopolymer material, holographic optical element, and optical device 华为技术有限公司 2023-04-25 CN claimed
US-20110043727-A1 ADHESIVE LAYER FOR MULTILAYER OPTICAL FILM 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-02-24 US claimed
EP-2263112-A2 ADHESIVE LAYER FOR MULTILAYER OPTICAL FILM 3M Innovative Properties Company (US) 2010-12-22 EP claimed
WO-2009145939-A1 ADHESIVE LAYER FOR MULTILAYER OPTICAL FILM 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-12-03 WO claimed
WO-2009145998-A2 ADHESIVE LAYER FOR MULTILAYER OPTICAL FILM 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-12-03 WO claimed
US-7376328-B2 Photosensitive resin composition for optical waveguide formation and optical waveguide JSR CORPORATION (JP) 2008-05-20 US claimed
US-7173072-B2 Radiation-curable resin composition for forming optical part and optical part JSR CORPORATION (JP) 2007-02-06 US claimed
EP-1699836-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL ARTICLES 3M Innovative Properties Company (US) 2006-09-13 EP claimed
WO-2005066228-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL ARTICLES 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-07-21 WO claimed
WO-2005062082-A1 BRIGHTNESS ENHANCING FILM COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-07-07 WO claimed
US-20050148735-A1 Polymerizable composition for optical articles 3M INNOVATIVE PROPERTIES COMPANY 2005-07-07 US claimed
EP-1495078-A2 PHOTOCURABLE RESIN COMPOSITION AND OPTICAL COMPONENT DSM IP Assets B.V. (NL) 2005-01-12 EP claimed
WO-2003076528-A2 PHOTOCURABLE RESIN COMPOSITION AND OPTICAL COMPONENT DSM IP ASSETS B.V. (NL) 2003-09-18 WO claimed
EP-0441383-B1 Use of a copolymer for the making of contact lenses MITSUBISHI RAYON CO (JP) 1996-05-08 EP claimed
US-5183870-A A curable polybutylene glycol di(meth)acrylate, a urethane or epoxy (meth)acrylate and a (meth)acrylate; heat and water resistance; impact strength; dyeability; workability MITSUBISHI RAYON CO., LTD (JP) 1993-02-02 US claimed
EP-0441383-A2 Use of a copolymer for the making of contact lenses MITSUBISHI RAYON CO., LTD. (JP) 1991-08-14 EP claimed
EP-4400223-A1 DIGITAL EMBOSSING CREATION METHOD Sakata INX Corporation (JP) 2024-07-17 EP disclosed
EP-4397726-A1 PHOTOCURABLE INK COMPOSITION FOR INKJET PRINTING Sakata INX Corporation (JP) 2024-07-10 EP disclosed
EP-0441383-A2 Use of a copolymer for the making of contact lenses MITSUBISHI RAYON CO., LTD. (JP) 1991-08-14 EP disclosed
US-4970135-A ACRYLIC ESTER POLYMERS MITSUBISHI RAYON CO., LTD. (JP) 1990-11-13 US disclosed