Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALPL | P05186 | 2/20 | 0.44 |
| ▸ | ALPI | P09923 | 2/20 | 0.44 |
| ▸ | ALPG | P10696 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1042823 | 0.92 | ALOX15 (0.47) | ALOX15HPGDALPLALPIALPG | |
| Acetone SCHEMBL1045404 | 0.90 | ALOX15 (0.46) | ALOX15HPGDALPLALPIALPG | |
| SCHEMBL7746 | 0.83 | ALOX15 (0.68) | ALOX15HPGDALPLALPIALPG | |
| SCHEMBL7805112 | 0.80 | PPARA (0.49) | ALOX15HPGDALPLALPIALPG | |
| SCHEMBL8225239 | 0.76 | SMN1; SMN2 (0.67) | ALOX15SMN1; SMN2RAB9AHTTL3MBTL1 | |
| Anisole SCHEMBL28851690 | 0.76 | ALOX15 (0.59) | ALOX15HPGDNPC1MAPTLMNA | |
| SCHEMBL12392890 | 0.76 | APP (0.42) | SMN1; SMN2ARL3MBTL1 | |
| SCHEMBL12392888 | 0.76 | MAOB (0.47) | MAPTLMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL12392895 | 0.76 | MAOB (0.47) | LMNASMN1; SMN2AR | |
| SCHEMBL12392883 | 0.76 | MAOB (0.47) | LMNASMN1; SMN2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2274434-A1 | 1, 2 ADDITION OF CARBONYL COMPOUNDS USING THE ENZYME YERE | Albert-Ludwigs-Universität Freiburg (DE) | 2011-01-19 | — | — | EP | disclosed |
| WO-2009138439-A1 | 1, 2 – ADDITION OF CARBONYL COMPOUNDS USING THE ENZYME YERE | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2009-11-19 | — | — | WO | disclosed |