Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1042823 | 0.98 | ALOX15 (0.47) | ALOX15MTNR1AMTNR1BARL3MBTL1 | |
| SCHEMBL1045116 | 0.90 | ALOX15 (0.49) | ALOX15MTNR1AMTNR1BARL3MBTL1 | |
| SCHEMBL7805112 | 0.85 | PPARA (0.49) | ALOX15MTNR1AMTNR1BARL3MBTL1 | |
| SCHEMBL12392886 | 0.81 | MAOA (0.47) | ARL3MBTL1PPARASSTR4MAOB | |
| SCHEMBL12392890 | 0.81 | APP (0.42) | ARL3MBTL1 | |
| SCHEMBL12392883 | 0.81 | MAOB (0.47) | ARSSTR4MAOB | |
| SCHEMBL12733054 | 0.81 | MAOA (0.47) | ARL3MBTL1PPARASSTR4MAOB | |
| SCHEMBL12392895 | 0.81 | MAOB (0.47) | ARSSTR4MAOB | |
| SCHEMBL12392888 | 0.81 | MAOB (0.47) | ARMAOB | |
| SCHEMBL12733066 | 0.80 | PTPN7 (0.53) | HPGDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2274434-A1 | 1, 2 ADDITION OF CARBONYL COMPOUNDS USING THE ENZYME YERE | Albert-Ludwigs-Universität Freiburg (DE) | 2011-01-19 | — | — | EP | disclosed |
| WO-2009138439-A1 | 1, 2 – ADDITION OF CARBONYL COMPOUNDS USING THE ENZYME YERE | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2009-11-19 | — | — | WO | disclosed |