Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GGT1 | P19440 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29009563 | 0.83 | AKR1C3 (0.55) | AKR1C3ALDH1A1CYP3A4ELANEMAPT | |
| SCHEMBL156451 | 0.82 | ALDH1A1 (0.65) | ALDH1A1CYP3A4ELANEMAPTMAPK1 | |
| SCHEMBL27596867 | 0.80 | AKR1C3 (0.52) | AKR1C3ALDH1A1CYP3A4ELANEMAPT | |
| SCHEMBL10137795 | 0.77 | AKR1C3 (0.61) | AKR1C3ALDH1A1ELANEMAPTGAA | |
| SCHEMBL700595 | 0.75 | AKR1C3 (0.85) | AKR1C3ALDH1A1MAPTGAAKDM4E | |
| SCHEMBL29447165 | 0.75 | AKR1C3 (0.85) | AKR1C3ALDH1A1MAPTGAAKDM4E | |
| SCHEMBL27324470 | 0.75 | AKR1C3 (0.59) | AKR1C3ALDH1A1ELANEMAPTGAA | |
| SCHEMBL822891 | 0.74 | AKR1C3 (0.68) | AKR1C3ALDH1A1ELANEMAPTGAA | |
| Acetic Acid Methyl Ester SCHEMBL28120666 | 0.74 | AKR1C3 (0.57) | AKR1C3ALDH1A1CYP3A4ELANEMAPT | |
| SCHEMBL26661026 | 0.74 | AKR1C3 (0.57) | AKR1C3ALDH1A1CYP3A4ELANEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0184233-B1 | DRUG DISPENSING WOUND DRESSING | THERMEDICS, INC. (US) | 1990-05-23 | — | — | EP | claimed |
| US-RE32991-E | Drug dispensing wound dressing | THERMEDICS, INC. (US) | 1989-07-18 | — | — | US | claimed |
| US-4614787-A | POLYURETHANE MATRIX | THERMEDICS, INC. (US) | 1986-09-30 | — | — | US | claimed |
| EP-0184233-A2 | Drug dispensing wound dressing | THERMEDICS, INC. (US) | 1986-06-11 | — | — | EP | claimed |