Sugi Predict

Sugi Predict / Compounds / SCHEMBL10137795

SCHEMBL10137795

SCHEMBL10137795

CC(C)C(=O)c1ccccc1C(=O)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ AKR1C3 P42330 3/20 0.61
▸ GAA P10253 1/20 0.52
▸ MAPT P10636 1/20 0.52
▸ BCL2 P10415 2/20 0.51
▸ MCL1 Q07820 2/20 0.51
▸ ALDH1A1 P00352 2/20 0.50
▸ CDC25B P30305 1/20 0.48
▸ ATM Q13315 1/20 0.48
▸ ELANE P08246 2/20 0.47
▸ HPGD P15428 1/20 0.47
▸ HTT P42858 1/20 0.47
▸ RAB9A P51151 1/20 0.47
▸ SMN1; SMN2 Q16637 1/20 0.47
▸ NPSR1 Q6W5P4 1/20 0.47
▸ POLB P06746 1/20 0.47
▸ NR4A1 P22736 1/20 0.47
▸ KMT2A Q03164 1/20 0.46
▸ MYC P01106 1/20 0.45
▸ GABRA1 P14867 1/20 0.44
▸ GABRB1 P18505 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27324470 0.86 AKR1C3 (0.59) AKR1C3GAAMAPTBCL2MCL1
SCHEMBL10308375 0.85 PDK2 (0.46) GAAMAPTBCL2MCL1ALDH1A1
SCHEMBL700595 0.82 AKR1C3 (0.85) AKR1C3GAAMAPTALDH1A1CDC25B
SCHEMBL29447165 0.82 AKR1C3 (0.85) AKR1C3GAAMAPTALDH1A1CDC25B
SCHEMBL5501608 0.81 ALDH1A1 (0.64) AKR1C3MAPTALDH1A1CDC25BATM
SCHEMBL28883310 0.80 AKR1C3 (0.81) AKR1C3GAAMAPTALDH1A1CDC25B
Fluoride SCHEMBL28319246 0.80 AKR1C3 (0.81) AKR1C3GAAMAPTALDH1A1CDC25B
SCHEMBL29009563 0.79 AKR1C3 (0.55) AKR1C3GAAMAPTALDH1A1CDC25B
SCHEMBL16222220 0.79 ALDH1A1 (0.61) GAAMAPTALDH1A1ATMELANE
SCHEMBL29163962 0.78 AKR1C3 (0.77) AKR1C3GAAMAPTALDH1A1CDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114478624-B Telomer of diethyl aluminum phosphinate and preparation method thereof 兰州瑞朴科技有限公司 2024-07-02 — — CN disclosed
CN-114478624-A Telomer of aluminum diethylphosphinate and preparation method thereof 兰州瑞朴科技有限公司 2022-05-13 — — CN disclosed
US-20190211184-A1 POLYCYCLIC GLYOXYLATES AS PHOTOINITIATORS IGM GROUP B.V. (NL) 2019-07-11 — — US disclosed
US-20170320833-A1 HEPATITIS C VIRUS INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2017-11-09 — — US disclosed
US-20170320833-A1 HEPATITIS C VIRUS INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2017-11-09 — — US disclosed
US-9758487-B2 Hepatitis C virus inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2017-09-12 — — US disclosed
US-9758487-B2 Hepatitis C virus inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2017-09-12 — — US disclosed
US-20170240755-A1 POLYCYCLIC PHOTOINITIATORS IGM GROUP B.V. (NL) 2017-08-24 — — US disclosed
US-20160311778-A1 Hepatitis C Virus Inhibitors BRISTOL-MYERS SQUIBB COMPANY 2016-10-27 — — US disclosed
US-9421192-B2 Hepatitis C virus inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2016-08-23 — — US disclosed
US-20090068140-A1 HEPATITIS C VIRUS INHIBITORS BRISTOL-MYERS SQUIBB COMPANY 2009-03-12 — — US disclosed
US-20080050336-A1 Hepatitis C Virus Inhibitors BRISTOL-MYERS SQUIBB COMPANY 2008-02-28 — — US disclosed
US-20070232549-A1 Novel peptides as NS3-serine protease inhibitors of hepatitis C virus SCHERING CORPORATION 2007-10-04 — — US disclosed
US-7244721-B2 Peptides as NS3-serine protease inhibitors of hepatitis C virus SCHERING CORPORATION (US) 2007-07-17 — — US disclosed
US-20070032433-A1 Novel peptides as NS3-serine protease inhibitors of hepatitis C virus SCHERING CORPORATION CORVAS INTERNATIONAL, LTD. 2007-02-08 — — US disclosed
US-7169760-B2 Peptides as NS3-serine protease inhibitors of hepatitis C virus SCHERING CORPORATION (US) 2007-01-30 — — US disclosed
CN-1747989-A Surface preparation of rubber for coatings or bonding. LORD CORP (US) 2006-03-15 — — CN disclosed
CN-1205185-C Nitrogen-containing cyclic compound and pharmaceutical composition containing the same EISAI CO LTD (JP) 2005-06-08 — — CN disclosed
CN-1395562-A Nitrogenous cyclic compounds and pharmaceutical compositions containing the same EISAI CO LTD (JP) 2003-02-05 — — CN disclosed
CN-1254346-A Calcitonin receptor-binding peptides DIATIDE INC (US) 2000-05-24 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070232549-A1 Novel peptides as NS3-serine protease inhibitors of hepatitis C virus HPN, TMPRSS15, VIP AKR1C3 1969/4885GAA 725/4885MAPT 4113/4885
US-20080050336-A1 Hepatitis C Virus Inhibitors HAVCR2, PYGL, HCCS AKR1C3 1685/4885GAA 223/4885MAPT 4065/4885
US-20090068140-A1 HEPATITIS C VIRUS INHIBITORS HAVCR2, PYGL, HCCS AKR1C3 1685/4885GAA 223/4885MAPT 4065/4885
US-20170240755-A1 POLYCYCLIC PHOTOINITIATORS C1R, C9, C5 AKR1C3 43/4885GAA 4856/4885MAPT 4615/4885
US-20170320833-A1 HEPATITIS C VIRUS INHIBITORS HAVCR2, PYGL, HCCS AKR1C3 1685/4885GAA 223/4885MAPT 4065/4885
US-20160311778-A1 Hepatitis C Virus Inhibitors HAVCR2, PYGL, HCCS AKR1C3 1685/4885GAA 223/4885MAPT 4065/4885
US-20070032433-A1 Novel peptides as NS3-serine protease inhibitors of hepatitis C virus HPN, TMPRSS15, VIP AKR1C3 1969/4885GAA 725/4885MAPT 4113/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.