Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | F13A1 | P00488 | 1/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10865713 | 0.87 | L3MBTL1 (0.66) | KDM4EF13A1HDAC3HDAC4HDAC1 | |
| SCHEMBL10451965 | 0.87 | KDM4E (0.64) | KDM4EF13A1HDAC3HDAC4HDAC1 | |
| SCHEMBL9661496 | 0.84 | SMN1; SMN2 (0.60) | KDM4EF13A1HDAC3HDAC4HDAC1 | |
| SCHEMBL10462585 | 0.84 | HDAC3 (0.53) | KDM4EF13A1HDAC3HDAC4HDAC1 | |
| SCHEMBL4867311 | 0.83 | ALDH1A1 (0.73) | KDM4EF13A1HDAC3HDAC4HDAC1 | |
| SCHEMBL6845396 | 0.83 | KDM4E (0.72) | KDM4EF13A1HDAC3HDAC4HDAC1 | |
| SCHEMBL10592850 | 0.82 | KDM4E (0.84) | KDM4EF13A1HDAC3HDAC4HDAC1 | |
| SCHEMBL6330555 | 0.82 | KDM4E (0.62) | KDM4EF13A1HDAC3HDAC4HDAC1 | |
| SCHEMBL11472615 | 0.82 | L3MBTL1 (0.55) | KDM4EF13A1HDAC3HDAC4HDAC1 | |
| SCHEMBL11481699 | 0.82 | L3MBTL1 (0.55) | KDM4EF13A1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127282-A1 | SUBSTITUTED 1,2, 4-TRIAZOLES AND METHODS OF USE | STINGINN LLC (US) | 2021-06-24 | — | — | WO | disclosed |
| US-4948809-A | TREATMENT OF AILMENTS DUE TO THROMBOCYTE AGGREGATION OR KIDNEY DYSFUNCTION | BOEHRINGER MANNHEIM GMBH (DE) | 1990-08-14 | — | — | US | disclosed |
| EP-0221344-B1 | SULPHONYL-PHENYL ALKYL AMINES, PROCESS FOR THEIR PREPARATION AND MEDICINES | Roche Diagnostics GmbH (DE) | 1990-05-23 | — | — | EP | disclosed |
| EP-0221344-A1 | Sulphonyl-phenyl alkyl amines, process for their preparation and medicines | Roche Diagnostics GmbH (DE) | 1987-05-13 | — | — | EP | disclosed |