Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CPB1 | P15086 | 1/20 | 0.42 |
| ▸ | CPA3 | P15088 | 1/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | TSPO | P30536 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10453045 | 0.84 | ABCB1 (0.50) | MEN1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL5654192 | 0.81 | TRPA1 (0.55) | MEN1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL8950842 | 0.79 | TSHR (0.44) | MEN1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL16932332 | 0.79 | KMT2A (0.49) | MEN1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL14541169 | 0.79 | TSHR (0.44) | MEN1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL17275362 | 0.79 | KMT2A (0.49) | MEN1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL8950839 | 0.79 | TSHR (0.44) | MEN1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL28150189 | 0.79 | KMT2A (0.49) | MEN1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL428101 | 0.78 | TSHR (0.46) | MEN1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL26989268 | 0.78 | TSHR (0.46) | MEN1KMT2AHPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990669-A | Optically active α-amino aldehydes, process for the preparation thereof, and the use thereof for the stereoselective preparation of optically active β-amino alcohols | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |