Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10452817 | 0.84 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ATAAR1HSD17B10 | |
| SCHEMBL5187444 | 0.84 | TAAR1 (0.72) | ALDH1A1MEN1KMT2ATAAR1HSD17B10 | |
| SCHEMBL5524577 | 0.84 | ALDH1A1 (0.79) | ALDH1A1MEN1KMT2ATAAR1HSD17B10 | |
| SCHEMBL9330609 | 0.84 | MEN1 (0.68) | ALDH1A1MEN1KMT2ATAAR1HSD17B10 | |
| SCHEMBL3915476 | 0.84 | PRMT1 (0.71) | ALDH1A1MEN1KMT2ATAAR1HSD17B10 | |
| SCHEMBL5187812 | 0.84 | TDP1 (0.67) | ALDH1A1MEN1KMT2ATAAR1HSD17B10 | |
| SCHEMBL29019309 | 0.81 | ALDH1A1 (0.84) | ALDH1A1MEN1KMT2ASIGMAR1SMN1; SMN2 | |
| SCHEMBL3913390 | 0.81 | TAAR1 (0.72) | ALDH1A1MEN1KMT2ATAAR1SMN1; SMN2 | |
| SCHEMBL5185902 | 0.81 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2ATAAR1HSD17B10 | |
| SCHEMBL5188475 | 0.81 | ALDH1A1 (0.81) | ALDH1A1MEN1KMT2ASMN1; SMN2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0221344-B1 | SULPHONYL-PHENYL ALKYL AMINES, PROCESS FOR THEIR PREPARATION AND MEDICINES | Roche Diagnostics GmbH (DE) | 1990-05-23 | — | — | EP | disclosed |
| EP-0221344-A1 | Sulphonyl-phenyl alkyl amines, process for their preparation and medicines | Roche Diagnostics GmbH (DE) | 1987-05-13 | — | — | EP | disclosed |