Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.79 |
| ▸ | MEN1 | O00255 | 2/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17974011 | 0.89 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL10452817 | 0.84 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ASMN1; SMN2TAAR1 | |
| SCHEMBL5187444 | 0.84 | TAAR1 (0.72) | ALDH1A1MEN1KMT2ASMN1; SMN2TAAR1 | |
| SCHEMBL10453046 | 0.84 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ASMN1; SMN2PPARG | |
| SCHEMBL9330609 | 0.84 | MEN1 (0.68) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL625181 | 0.84 | ALDH1A1 (0.84) | ALDH1A1MEN1KMT2APPARGTAAR1 | |
| SCHEMBL5187812 | 0.84 | TDP1 (0.67) | ALDH1A1MEN1KMT2ASMN1; SMN2TAAR1 | |
| SCHEMBL5188475 | 0.84 | ALDH1A1 (0.81) | ALDH1A1MEN1KMT2ASMN1; SMN2PPARG | |
| SCHEMBL6803886 | 0.81 | ALDH1A1 (0.84) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL29260042 | 0.81 | ALDH1A1 (0.84) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7179832-B2 | Glycogen synthase kinase 3β inhibitor, composition and process for the preparation thereof | CRYSTALGENOMICS, INC. (KR) | 2007-02-20 | — | — | US | disclosed |
| US-20060079521-A1 | Glycogen synthase kinase 3beta inhibitor, composition and process for the preparation thereof | CRYSTALGENOMICS, INC. (KR) | 2006-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060079521-A1 | Glycogen synthase kinase 3beta inhibitor, composition and process for the preparation thereof | GSK3B, GSK3A, GYS2 | ALDH1A1 3930/4885MEN1 4192/4885KMT2A 2546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.