Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10453683 | 0.81 | MAP2K1 (0.48) | MAP2K1NPC1EPHX2ALDH1A1SMN1; SMN2 | |
| SCHEMBL10453674 | 0.80 | EPHX2 (0.50) | EPHX2SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL10453693 | 0.78 | EPHX1 (0.50) | MAP2K1NPC1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL9527776 | 0.78 | EPHX1 (0.47) | MAP2K1NPC1MEN1KMT2ARAB9A | |
| SCHEMBL15376425 | 0.75 | EPHX2 (0.70) | NPC1EPHX2ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL10453530 | 0.75 | KMT2A (0.50) | NPC1EPHX2ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL10453531 | 0.75 | KMT2A (0.50) | NPC1EPHX2ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL11328254 | 0.73 | EPHX2 (0.34) | MAP2K1EPHX2ALDH1A1KMT2ACYP2D6 | |
| SCHEMBL694044 | 0.72 | MAPT (0.74) | NPC1EPHX2ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL2650184 | 0.70 | MAPT (0.71) | NPC1EPHX2ALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4921939-A | GUANIDINE AND AMIDINE COMPOUNDS CONTAINING ACID GROUPS | UNIVERSITE CLAUDE BERNARD -LYON 1 (FR) | 1990-05-01 | — | — | US | disclosed |
| EP-0241395-A2 | Sweeteners derived from n-phenylguanidinoacetic and n-phenylethananamidinacetic acids, and compositions containing such sweeteners | UNIVERSITE CLAUDE BERNARD - LYON 1 (FR) | 1987-10-14 | — | — | EP | disclosed |