Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.37 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.37 |
| ▸ | ABCC9 | O60706 | 3/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 3/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10452542 | 1.00 | EPHX1 (0.47) | EPHX1TSHRPAX8NAMPTMAOA | |
| SCHEMBL10453683 | 0.83 | MAP2K1 (0.48) | EPHX1KMT2ANPC1RAB9AMAP2K1 | |
| SCHEMBL10453674 | 0.82 | EPHX2 (0.50) | EPHX1TSHRKMT2ARAB9AMEN1 | |
| SCHEMBL10453589 | 0.80 | EPHX1 (0.50) | EPHX1TSHRPAX8MAOAMAOB | |
| SCHEMBL9529344 | 0.80 | EPHX1 (0.50) | EPHX1TSHRPAX8MAOAMAOB | |
| SCHEMBL9528819 | 0.80 | EPHX1 (0.50) | EPHX1TSHRPAX8MAOAMAOB | |
| SCHEMBL10453855 | 0.80 | EPHX1 (0.50) | EPHX1TSHRPAX8MAOAMAOB | |
| SCHEMBL10453701 | 0.78 | ABCC9 (0.46) | TSHRKMT2ARAB9ASAE1UBA2 | |
| SCHEMBL10453693 | 0.78 | EPHX1 (0.50) | EPHX1NAMPTKMT2ANPC1RAB9A | |
| SCHEMBL10453532 | 0.78 | MAP2K1 (0.55) | NAMPTKMT2ANPC1RAB9AMAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299533-B1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1993-04-07 | — | — | EP | disclosed |
| WO-1989000563-A1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (US) | 1989-01-26 | — | — | WO | disclosed |
| EP-0299533-A2 | High potency sweetening agents | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1989-01-18 | — | — | EP | disclosed |