Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10453530 | 1.00 | KMT2A (0.50) | KMT2AMEN1MMP13NPC1SMN1; SMN2 | |
| SCHEMBL10453680 | 0.81 | SMN1; SMN2 (0.44) | KMT2AMEN1NPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10453682 | 0.81 | SMN1; SMN2 (0.44) | KMT2AMEN1NPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10453672 | 0.81 | EPHX1 (0.50) | KMT2ANPC1SMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL10453673 | 0.81 | EPHX1 (0.50) | KMT2ANPC1SMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL10453364 | 0.79 | KMT2A (0.46) | KMT2AMEN1MMP13NPC1SMN1; SMN2 | |
| SCHEMBL10453691 | 0.79 | ALDH1A1 (0.55) | KMT2AMEN1NPC1ALDH1A1L3MBTL1 | |
| SCHEMBL10453692 | 0.79 | ALDH1A1 (0.55) | KMT2AMEN1NPC1ALDH1A1L3MBTL1 | |
| SCHEMBL9527772 | 0.78 | NOS3 (0.40) | KMT2AMEN1NPC1ALDH1A1EPHX2 | |
| SCHEMBL9527770 | 0.78 | NOS3 (0.40) | KMT2AMEN1NPC1ALDH1A1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4921939-A | GUANIDINE AND AMIDINE COMPOUNDS CONTAINING ACID GROUPS | UNIVERSITE CLAUDE BERNARD -LYON 1 (FR) | 1990-05-01 | — | — | US | disclosed |
| EP-0241395-A2 | Sweeteners derived from n-phenylguanidinoacetic and n-phenylethananamidinacetic acids, and compositions containing such sweeteners | UNIVERSITE CLAUDE BERNARD - LYON 1 (FR) | 1987-10-14 | — | — | EP | disclosed |