SCHEMBL10453983

SCHEMBL10453983

CON(C)C(=O)Nc1ccc(C(C)C)c(Cl)c1

nearest known ligand 0.67

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 3/20 0.67
▸ MEN1 O00255 2/20 0.67
▸ PKM P14618 1/20 0.60
▸ RAB9A P51151 1/20 0.60
▸ TDP1 Q9NUW8 1/20 0.52
▸ APEX1 P27695 1/20 0.50
▸ HPGD P15428 3/20 0.42
▸ RORC P51449 2/20 0.42
▸ ALDH1A1 P00352 2/20 0.40
▸ KDM4E B2RXH2 1/20 0.40
▸ GLA P06280 1/20 0.40
▸ GAA P10253 1/20 0.40
▸ TSHR P16473 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11266713 0.85 APEX1 (0.69) KMT2AMEN1TDP1APEX1TSHR
Linuron SCHEMBL27260336 0.84 KMT2A (0.76) KMT2AMEN1PKMRAB9ATDP1
Linuron SCHEMBL56566 0.84 KMT2A (0.76) KMT2AMEN1PKMRAB9ATDP1
Linuron SCHEMBL8406948 0.84 KMT2A (0.76) KMT2AMEN1PKMRAB9ATDP1
Linuron SCHEMBL28168150 0.81 KMT2A (0.72) KMT2AMEN1PKMRAB9ATDP1
SCHEMBL11408105 0.81 KMT2A (0.72) KMT2AMEN1PKMRAB9ATDP1
SCHEMBL11804441 0.81 RORC (0.67) KMT2AMEN1PKMRAB9ATDP1
SCHEMBL9633496 0.81 SMN1; SMN2 (0.47) HPGDRORC
SCHEMBL10671909 0.80 MEN1 (0.53) KMT2AMEN1PKMRAB9ATDP1
Linuron SCHEMBL9057322 0.80 APEX1 (0.79) KMT2AMEN1PKMRAB9ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0157171-B1 HERBICIDAL AGENTS HOECHST AKTIENGESELLSCHAFT (DE) 1990-09-19 — — EP claimed
US-4789747-A BROAD LEAF PLANTS, GRASSES, WEEDS BASF AKTIENGESELLSCHAFT (DE) 1988-12-06 — — US disclosed
US-4761175-A M-anilido-urethanes and herbicides containing these compounds BASF AKTIENGESELLSCHAFT (DE) 1988-08-02 — — US disclosed
US-4744812-A HALOGENATED DIPHENYL ETHER BASF AKTIENGESELLSCHAFT (DE) 1988-05-17 — — US disclosed
US-4645526-A SYNERGISTIC MIX OF UREA-BASED COMPONENT WITH BENZOXAZOLYL-PHENOXY-PROPIONATE-TYPE MATERIAL HOECHST AKTIENGESELLSCHAFT (DE) 1987-02-24 — — US disclosed
US-4632696-A POSTEMERGENCE, PREEMERGENCE APPLICATIONS BASF AKTIENGESELLSCHAFT (DE) 1986-12-30 — — US disclosed
US-4568383-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1986-02-04 — — US disclosed
US-4523942-A 4H-3,1-Benzoxazine derivatives, compositions and herbicidal use BASF AKTIENGESELLSCHAFT (DE) 1985-06-18 — — US disclosed
US-4515623-A APPLYING TO PLANTS, SEEDS OR SOILS BASF AKTIENGESELLSCHAFT (DE) 1985-05-07 — — US disclosed
US-4505741-A Herbicides containing-3-aryl-5-methylpyrazole-4-carboxylic acid esters, their manufacture and use BASF AKTIENGESELLSCHAFT (DE) 1985-03-19 — — US disclosed
US-4401821-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1983-08-30 — — US disclosed
US-4396418-A N-Aryl(thio)carbamates, the manufacture thereof, and the use thereof for combating unwanted plant growth BASF AKTIENGESELLSCHAFT (DE) 1983-08-02 — — US disclosed
US-4385924-A 1,2-Oxazolyl alkyl carbamates, and their use as herbicides BASF AKTIENGESELLSCHAFT (DE) 1983-05-31 — — US disclosed
US-4363651-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1982-12-14 — — US disclosed
US-4360672-A Substituted phenoxyphenyl pyridazones, their preparation, and their use as herbicides BASF AKTIENGESELLSCHAFT (DE) 1982-11-23 — — US disclosed
US-4343648-A 6H-1,2,4,6-THIATRIAZINE-1,1-DIOXIDES BASF AKTIENGESELLSCHAFT (DE) 1982-08-10 — — US disclosed
US-4340418-A Herbicidal agents based on N-azolylmethylacetanilides and cyclohexane-1,3-dione derivatives BASF AKTIENGESELLSCHAFT (DE) 1982-07-20 — — US disclosed
US-4321371-A Substituted N-benzoylanthranilic acid derivatives and their anhydro compounds BASF AKTIENGESELLSCHAFT (DE) 1982-03-23 — — US disclosed
US-4316014-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1982-02-16 — — US disclosed
US-4309210-A HERBICIDE AND SAFENING AGENT CIBA-GEIGY CORPORATION (US) 1982-01-05 — — US disclosed
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