Linuron

Linuron

SCHEMBL9057322

CN(C)C(=O)Nc1ccc(Cl)c(Cl)c1.CON(C)C(=O)Nc1ccc(Cl)c(Cl)c1

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.79
KMT2A Q03164 4/20 0.70
MEN1 O00255 3/20 0.70
RAB9A P51151 2/20 0.63
PKM P14618 1/20 0.63
TDP1 Q9NUW8 1/20 0.55
TSHR P16473 1/20 0.53
EPHX1 P07099 1/20 0.51
EPHX2 P34913 1/20 0.51
ALDH1A1 P00352 2/20 0.50
HPGD P15428 2/20 0.50
KDM4E B2RXH2 1/20 0.50
GLA P06280 1/20 0.50
GAA P10253 1/20 0.50
CYP3A4 P08684 2/20 0.49
L3MBTL1 Q9Y468 1/20 0.48
CA2 P00918 1/20 0.47
CA4 P22748 1/20 0.47
CA5A P35218 1/20 0.47
CA9 Q16790 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Linuron SCHEMBL56566 0.95 KMT2A (0.76) APEX1KMT2AMEN1RAB9APKM
Linuron SCHEMBL8406948 0.95 KMT2A (0.76) APEX1KMT2AMEN1RAB9APKM
Linuron SCHEMBL27260336 0.95 KMT2A (0.76) APEX1KMT2AMEN1RAB9APKM
Linuron SCHEMBL9419428 0.95 PKM (0.74) APEX1KMT2AMEN1RAB9APKM
Linuron SCHEMBL28168150 0.93 KMT2A (0.72) APEX1KMT2AMEN1RAB9APKM
Chloroxuron SCHEMBL8602342 0.90 PKM (0.67) APEX1KMT2AMEN1RAB9APKM
Linuron SCHEMBL8780339 0.90 PKM (0.80) APEX1KMT2AMEN1RAB9APKM
Dcmu SCHEMBL7279 0.89 APEX1 (1.00) APEX1KMT2AMEN1RAB9APKM
Dcmu SCHEMBL29349863 0.89 APEX1 (1.00) APEX1KMT2AMEN1RAB9APKM
Dcmu SCHEMBL1352353 0.89 APEX1 (1.00) APEX1KMT2AMEN1RAB9APKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0619946-B1 Herbicidal composition for upland farming and weeding method NIHON NOHYAKU CO LTD (JP) 1996-06-05 EP claimed
EP-0619946-A1 Herbicidal composition for upland farming and weeding method NIHON NOHYAKU CO., LTD. (JP) 1994-10-19 EP claimed
US-4255182-A PRE- AND POSTEMERGENCE HERBICIDES VELSICOL CHEMICAL CORPORATION (US) 1981-03-10 US disclosed
US-3948967-A HERBICIDE, FUNGICIDE VELSICOL CHEMICAL CORPORATION (US) 1976-04-06 US disclosed