SCHEMBL10454139

SCHEMBL10454139

COC(=O)c1cnn(-c2ccccc2)c1/N=N/c1c(C)nn(-c2nc(O)nc(-n3nc(C)c(/N=N/c4c(C(=O)OC)cnn4-c4ccccc4)c3N)n2)c1N

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HPGD P15428 4/20 0.46
▸ RAB9A P51151 9/20 0.45
▸ NPC1 O15118 8/20 0.45
▸ SMN1; SMN2 Q16637 7/20 0.45
▸ MAPT P10636 6/20 0.45
▸ TDP1 Q9NUW8 5/20 0.45
▸ ALDH1A1 P00352 4/20 0.45
▸ MAPK1 P28482 3/20 0.44
▸ L3MBTL1 Q9Y468 3/20 0.44
▸ KMT2A Q03164 3/20 0.44
▸ MEN1 O00255 2/20 0.44
▸ ALOX12 P18054 1/20 0.44
▸ HTT P42858 1/20 0.44
▸ LMNA P02545 1/20 0.41
▸ GAA P10253 1/20 0.40
▸ GPR35 Q9HC97 3/20 0.39
▸ GPR55 Q9Y2T6 2/20 0.39
▸ NPSR1 Q6W5P4 1/20 0.39
▸ NFKB1 P19838 1/20 0.39
▸ NFKB2 Q00653 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13159985 0.95 HPGD (0.42) HPGDRAB9ANPC1SMN1; SMN2MAPT
SCHEMBL9972805 0.94 HPGD (0.41) HPGDRAB9ANPC1SMN1; SMN2MAPT
SCHEMBL20411816 0.93 HPGD (0.46) HPGDRAB9ANPC1SMN1; SMN2MAPT
SCHEMBL12759192 0.93 HPGD (0.40) HPGDRAB9ANPC1SMN1; SMN2MAPT
SCHEMBL10332024 0.91 RAB9A (0.48) HPGDRAB9ANPC1SMN1; SMN2MAPT
SCHEMBL20311542 0.91 HPGD (0.38) HPGDRAB9ANPC1SMN1; SMN2MAPT
SCHEMBL20411815 0.88 HPGD (0.48) HPGDRAB9ANPC1SMN1; SMN2MAPT
SCHEMBL15730957 0.87 HPGD (0.41) HPGDRAB9ANPC1SMN1; SMN2MAPT
SCHEMBL10452739 0.86 KMT2A (0.39) HPGDRAB9ANPC1SMN1; SMN2MAPT
SCHEMBL14845499 0.86 ALDH1A1 (0.40) HPGDRAB9ANPC1SMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2154209-B1 Water-based ink composition for inkjet recording FUJIFILM CORP (JP) 2014-12-31 — — EP disclosed
US-8835531-B2 Water-based ink composition for inkjet recording FUJIFILM CORPORATION (JP) 2014-09-16 — — US disclosed
US-8835531-B2 Water-based ink composition for inkjet recording FUJIFILM CORPORATION (JP) 2014-09-16 — — US disclosed
EP-2370530-B1 INK SET, RECORDED MATERIAL AND PRINTED MATERIAL FUJIFILM CORP (JP) 2014-02-12 — — EP disclosed
US-8641785-B2 Aqueous pigment dispersion and aqueous ink for inkjet recording FUJIFILM CORPORATION (JP) 2014-02-04 — — US disclosed
US-8580025-B2 Ink set, recording method, recorded material and printed material FUJIFILM CORPORATION (JP) 2013-11-12 — — US disclosed
US-8500897-B2 Ink set, recorded material and printed material FUJIFILM CORPORATION (JP) 2013-08-06 — — US disclosed
US-8426495-B2 Radiation-curable ink composition for inkjet recording, inkjet recording method, and printed matter FUJIFILM CORPORATION (JP) 2013-04-23 — — US disclosed
US-8415409-B2 Radiation-curable ink composition for inkjet recording, inkjet recording method, and printed matter FUJIFILM CORPORATION (JP) 2013-04-09 — — US disclosed
US-8415409-B2 Radiation-curable ink composition for inkjet recording, inkjet recording method, and printed matter FUJIFILM CORPORATION (JP) 2013-04-09 — — US disclosed
US-8393725-B2 Ink set and image forming method FUJIFILM CORPORATION (JP) 2013-03-12 — — US disclosed
US-8393725-B2 Ink set and image forming method FUJIFILM CORPORATION (JP) 2013-03-12 — — US disclosed
US-8348408-B2 Ink set and image forming method FUJIFILM CORPORATION (JP) 2013-01-08 — — US disclosed
US-8222326-B2 Water-based ink composition for inkjet recording FUJIFILM CORPORATION (JP) 2012-07-17 — — US disclosed
US-20110050790-A1 INK SET AND IMAGE FORMING METHOD FUJIFILM CORPORATION (JP) 2011-03-03 — — US disclosed
US-20110050789-A1 INK SET AND IMAGE FORMING METHOD FUJIFILM CORPORATION (JP) 2011-03-03 — — US disclosed
US-20100240812-A1 OIL-BASED INKJET RECORDING INK FUJIFILM CORPORATION (JP) 2010-09-23 — — US disclosed
US-20100221506-A1 RADIATION-CURABLE INK COMPOSITION FOR INKJET RECORDING,INKJET RECORDING METHOD, AND PRINTED MATTER FUJIFILM CORPORATION (JP) 2010-09-02 — — US disclosed
US-20100222472-A1 WATER-BASED INK COMPOSITION FOR INKJET RECORDING FUJIFILM CORPORATION (JP) 2010-09-02 — — US disclosed
US-20100160504-A1 WATER-BASED INK COMPOSITION FOR INKJET RECORDING FUJIFILM CORPORATION (JP) 2010-06-24 — — US disclosed
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