Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 3/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9614155 | 1.00 | TBXAS1 (0.45) | TBXAS1SIGMAR1KDM1AMTNR1AMTNR1B | |
| SCHEMBL29118769 | 0.92 | TBXAS1 (0.53) | TBXAS1SIGMAR1 | |
| SCHEMBL29633520 | 0.88 | TBXAS1 (0.41) | TBXAS1KDM1AMTNR1AMTNR1BCYP1A2 | |
| SCHEMBL30705332 | 0.85 | KDM1A (0.44) | TBXAS1KDM1AMTNR1AMTNR1BCYP1A2 | |
| SCHEMBL1053054 | 0.84 | TBXAS1 (0.45) | TBXAS1SIGMAR1KDM1ACYP1A2 | |
| SCHEMBL21462939 | 0.84 | TBXAS1 (0.45) | TBXAS1SIGMAR1KDM1ACYP1A2 | |
| SCHEMBL1053053 | 0.84 | TBXAS1 (0.45) | TBXAS1SIGMAR1KDM1ACYP1A2 | |
| SCHEMBL2768526 | 0.82 | TBXAS1 (0.48) | TBXAS1 | |
| SCHEMBL2240176 | 0.82 | ALDH1A1 (0.36) | TBXAS1 | |
| SCHEMBL2240179 | 0.82 | ALDH1A1 (0.36) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0111105-B1 | UNSATURATED AROMATIC AMIDES AS PESTICIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1990-12-05 | — | — | EP | disclosed |
| US-4931469-A | APPLYING UNSATURATED PHENYL AMIDES; FOR ACARINA | BURROUGHS WELLCOME CO. (US) | 1990-06-05 | — | — | US | disclosed |
| US-4855086-A | MITICIDES, INSECTICIDES | BURROUGHS WELLCOME CO. (US) | 1989-08-08 | — | — | US | disclosed |
| EP-0111105-A2 | Unsaturated aromatic amides as pesticides | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-06-20 | — | — | EP | disclosed |