Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP12 | P39900 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 5/20 | 0.41 |
| ▸ | HTR2C | P28335 | 4/20 | 0.41 |
| ▸ | HTR2B | P41595 | 4/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1276464 | 0.82 | CYP1A2 (0.56) | MMP2MMP12CA12CA1CA2 | |
| SCHEMBL8706112 | 0.81 | CYP1A2 (0.44) | MMP2MMP12CA12CA1CA2 | |
| SCHEMBL1460921 | 0.77 | NPSR1 (0.45) | MMP2MMP12CA12CA1CA2 | |
| SCHEMBL1460918 | 0.77 | NPSR1 (0.45) | MMP2MMP12CA12CA1CA2 | |
| SCHEMBL5243364 | 0.75 | NPSR1 (0.53) | MMP2MMP12CA12CA1CA2 | |
| SCHEMBL3660905 | 0.74 | CYP1A2 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31006227 | 0.74 | HTR2A (0.45) | MMP2MMP12CA12CA1CA2 | |
| SCHEMBL12267719 | 0.73 | NPSR1 (0.47) | MMP2MMP12CA12CA1CA2 | |
| SCHEMBL19359277 | 0.73 | MMP2 (0.61) | MMP2MMP12CA12CA1CA2 | |
| SCHEMBL13259162 | 0.73 | KDM4E (0.51) | MMP2MMP12CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0111105-B1 | UNSATURATED AROMATIC AMIDES AS PESTICIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1990-12-05 | — | — | EP | disclosed |
| US-4931469-A | APPLYING UNSATURATED PHENYL AMIDES; FOR ACARINA | BURROUGHS WELLCOME CO. (US) | 1990-06-05 | — | — | US | disclosed |
| US-4855086-A | MITICIDES, INSECTICIDES | BURROUGHS WELLCOME CO. (US) | 1989-08-08 | — | — | US | disclosed |
| EP-0111105-A2 | Unsaturated aromatic amides as pesticides | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-06-20 | — | — | EP | disclosed |