Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 4/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | HTR2B | P41595 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1460918 | 1.00 | NPSR1 (0.45) | NPSR1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL18980593 | 0.83 | APP (0.41) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL18980591 | 0.83 | APP (0.41) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL18980706 | 0.81 | RARB (0.36) | CYP2C9CYP2C19MMP2MMP12KCNH2 | |
| SCHEMBL18980704 | 0.81 | RARB (0.36) | CYP2C9CYP2C19MMP2MMP12KCNH2 | |
| SCHEMBL18980825 | 0.80 | KCNH2 (0.33) | KCNH2 | |
| SCHEMBL18980823 | 0.80 | KCNH2 (0.33) | KCNH2 | |
| SCHEMBL5243364 | 0.78 | NPSR1 (0.53) | NPSR1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL1276464 | 0.78 | CYP1A2 (0.56) | NPSR1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10454439 | 0.77 | MMP2 (0.44) | NPSR1CYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2482978-B1 | HETEROGENEOUS RHODIUM METAL CATALYSTS | UNIV ALBERTA (CA) | 2018-05-09 | — | — | EP | disclosed |
| US-8962516-B2 | Heterogeneous rhodium metal catalysts | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (US) | 2015-02-24 | — | — | US | disclosed |
| US-20130053576-A1 | HETEROGENEOUS RHODIUM METAL CATALYSTS | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA | 2013-02-28 | — | — | US | disclosed |
| EP-2482978-A1 | HETEROGENEOUS RHODIUM METAL CATALYSTS | The Governors Of The University Of Alberta (CA) | 2012-08-08 | — | — | EP | disclosed |
| WO-2011035445-A1 | HETEROGENEOUS RHODIUM METAL CATALYSTS | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2011-03-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053576-A1 | HETEROGENEOUS RHODIUM METAL CATALYSTS | RRM2, RRM2B, RRS1 | NPSR1 688/4885CYP1A2 2950/4885CYP3A4 2854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.