Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10454603 | 1.00 | TRPA1 (0.46) | TRPA1TAAR1SIGMAR1SLC6A2MAOA | |
| SCHEMBL27675011 | 0.90 | MME (0.42) | CYP2D6CYP1A2 | |
| SCHEMBL27466806 | 0.83 | ACACB (0.36) | TAAR1SLC6A2CYP2A6CYP1A2 | |
| SCHEMBL27489801 | 0.81 | IDO1 (0.42) | TAAR1CYP2D6MEN1KMT2ATSHR | |
| SCHEMBL22190437 | 0.79 | HTR2A (0.59) | TAAR1SIGMAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL21569429 | 0.79 | HTR2A (0.59) | TAAR1SIGMAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL4785594 | 0.76 | SIGMAR1 (0.64) | TRPA1TAAR1SIGMAR1SLC6A2MAOA | |
| SCHEMBL25209356 | 0.76 | TAAR1 (0.53) | TRPA1TAAR1SIGMAR1SLC6A2MAOA | |
| SCHEMBL1071466 | 0.76 | TAAR1 (0.48) | TRPA1TAAR1SIGMAR1SLC6A2MAOA | |
| SCHEMBL11518916 | 0.76 | TAAR1 (0.48) | TRPA1TAAR1SIGMAR1SLC6A2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0111105-B1 | UNSATURATED AROMATIC AMIDES AS PESTICIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1990-12-05 | — | — | EP | disclosed |
| US-4931469-A | APPLYING UNSATURATED PHENYL AMIDES; FOR ACARINA | BURROUGHS WELLCOME CO. (US) | 1990-06-05 | — | — | US | disclosed |
| US-4855086-A | MITICIDES, INSECTICIDES | BURROUGHS WELLCOME CO. (US) | 1989-08-08 | — | — | US | disclosed |