SCHEMBL10454829

SCHEMBL10454829

O=P(O)(O)C(c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACP3 P15309 10/20 0.59
CA12 O43570 2/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
MMP2 P08253 1/20 0.48
PGK1 P00558 2/20 0.46
PGK2 P07205 2/20 0.46
ESR1 P03372 5/20 0.44
ESR2 Q92731 4/20 0.44
PDCD1 Q15116 1/20 0.44
CD274 Q9NZQ7 1/20 0.44
LMNA P02545 2/20 0.40
CYP3A4 P08684 2/20 0.40
MAPT P10636 2/20 0.40
ALOX15 P16050 2/20 0.40
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
NPC1 O15118 1/20 0.40
GMNN O75496 1/20 0.40
ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL4616870 0.84 ACP3 (0.68) ACP3CA12CA1CA2PGK1
SCHEMBL5936840 0.80 SRC (0.62) ACP3CA12CA1CA2MMP2
SCHEMBL19638012 0.78 ACP3 (0.58) ACP3CA12CA2MMP2PGK1
SCHEMBL777805 0.78 ACP3 (0.57) ACP3CA12MMP2PGK1PGK2
SCHEMBL16859932 0.78 ACP3 (0.58) ACP3CA12CA1MMP2PGK1
SCHEMBL16931008 0.78 ACP3 (0.57) ACP3PGK1PGK2MAPTMEN1
SCHEMBL10252598 0.78 PGK1 (0.61) CA12CA1CA2MMP2PGK1
SCHEMBL232244 0.77 ACP3 (0.79) ACP3PGK1PGK2
Bisphenol A SCHEMBL29012695 0.76 ACP3 (0.59) ACP3ESR1ESR2LMNACYP3A4
SCHEMBL2199107 0.76 ESR1 (0.52) CA12CA1CA2MMP2PGK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4970249-A POLYPHOSPHONATES BAYER AKTIENGESELLSCHAFT (DE) 1990-11-13 US claimed