Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 5/20 | 0.61 |
| ▸ | PGK2 | P07205 | 5/20 | 0.61 |
| ▸ | GRM8 | O00222 | 1/20 | 0.49 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11208020 | 0.90 | PGK1 (0.71) | PGK1PGK2PTPN5 | |
| SCHEMBL11078378 | 0.79 | PGK1 (0.59) | PGK1PGK2CA12CA2MMP2 | |
| SCHEMBL744283 | 0.79 | PGK1 (0.59) | PGK1PGK2GRM8GRM4PTPN5 | |
| (4-Chlorophenyl)(Hydroxy)Methylphosphonic Acid SCHEMBL5746553 | 0.79 | PGK1 (0.59) | PGK1PGK2CA12CA2MMP2 | |
| SCHEMBL11079769 | 0.79 | PGK1 (0.59) | PGK1PGK2PTPN5HIF1A | |
| SCHEMBL11080198 | 0.79 | PGK1 (0.59) | PGK1PGK2CA12CA1MMP2 | |
| SCHEMBL5743524 | 0.79 | PGK1 (0.59) | PGK1PGK2CA12CA1MMP2 | |
| SCHEMBL11082211 | 0.79 | PGK1 (0.59) | PGK1PGK2CA12MMP2PTPN5 | |
| (4-Chlorophenyl)(Hydroxy)Methylphosphonic Acid SCHEMBL292744 | 0.79 | PGK1 (0.59) | PGK1PGK2CA12CA2MMP2 | |
| SCHEMBL10454829 | 0.78 | ACP3 (0.59) | PGK1PGK2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771548-B1 | USE OF DENDRIMERS TO STIMULATE CELL GROWTH | CENTRE NAT RECH SCIENT (FR) | 2012-06-27 | — | — | EP | disclosed |