SCHEMBL10455151

SCHEMBL10455151

CNS(=O)(=O)c1cc(Br)c(Br)c(Br)c1Br

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.37
ALDH1A1 P00352 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
GAA P10253 2/20 0.33
MAPT P10636 1/20 0.33
TSHR P16473 1/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA3 P07451 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA13 Q8N1Q1 1/20 0.32
CA14 Q9ULX7 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9577139 0.80 MAPT (0.41) LMNAALDH1A1SMN1; SMN2MAPTPOLB
SCHEMBL9577227 0.79 LMNA (0.40) LMNAL3MBTL1ALDH1A1SMN1; SMN2GAA
SCHEMBL9577198 0.79 SMN1; SMN2 (0.47) ALDH1A1SMN1; SMN2GAACYP1A2
SCHEMBL9577117 0.76 HTT (0.49) LMNAALDH1A1SMN1; SMN2GAATSHR
SCHEMBL28555485 0.76 CA1 (0.35) CA12CA1CA2CA3CA4
SCHEMBL10455208 0.76 RECQL (0.45) LMNAL3MBTL1ALDH1A1SMN1; SMN2GAA
SCHEMBL6150496 0.75 TDP1 (0.39) CA1CA2CA3CA4CA6
SCHEMBL9577203 0.73 MCL1 (0.43) CA1CA2CA9
SCHEMBL30876277 0.72 ZAP70 (0.38) LMNAL3MBTL1ALDH1A1CA12CA1
SCHEMBL11806410 0.71 TDP1 (0.36) MAPTCA12CA1CA2CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4957957-A Polymer compositions containing aromatic sulfonamide ETHYL CORPORATION (US) 1990-09-18 US disclosed