Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA3 | P07451 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA6 | P23280 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.36 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9577233 | 0.82 | ALDH1A1 (0.45) | LMNAALDH1A1SMN1; SMN2GAAL3MBTL1 | |
| SCHEMBL10455151 | 0.79 | LMNA (0.40) | LMNAALDH1A1SMN1; SMN2GAAL3MBTL1 | |
| SCHEMBL10455205 | 0.79 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2GAACA12CA1 | |
| SCHEMBL9577212 | 0.78 | HTT (0.50) | ALDH1A1SMN1; SMN2GAACA12CA1 | |
| SCHEMBL9577096 | 0.77 | EDNRA (0.38) | ALDH1A1HTTEDNRBEDNRA | |
| SCHEMBL9577188 | 0.76 | MCL1 (0.35) | CA1CA2HTTEDNRBEDNRA | |
| SCHEMBL9577102 | 0.76 | MCL1 (0.35) | CA1CA2HTTEDNRBEDNRA | |
| SCHEMBL9577125 | 0.76 | RECQL (0.49) | ALDH1A1L3MBTL1CA12CA1CA2 | |
| SCHEMBL7031097 | 0.76 | L3MBTL1 (0.38) | ALDH1A1SMN1; SMN2L3MBTL1CA1CA2 | |
| SCHEMBL30388332 | 0.75 | CA2 (0.36) | GAACA1CA2CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264474-A | Plasticizing thermoplastic or thermosetting resins with sulfonamide compounds | MTM AMERICAS INC. (US) | 1993-11-23 | — | — | US | disclosed |
| US-4957957-A | Polymer compositions containing aromatic sulfonamide | ETHYL CORPORATION (US) | 1990-09-18 | — | — | US | disclosed |