Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 7/20 | 0.44 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | ACSL1 | P33121 | 4/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | ACSL3 | O95573 | 1/20 | 0.37 |
| ▸ | ACSL6 | Q9UKU0 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10455756 | 0.85 | ELANE (0.42) | S1PR5ELANEGAAAKR1C3AKR1C1 | |
| SCHEMBL10455661 | 0.84 | S1PR5 (0.43) | S1PR5ACSL1ACSL3ACSL6 | |
| SCHEMBL10455499 | 0.80 | RAB9A (0.43) | POLB | |
| SCHEMBL10455781 | 0.80 | ELANE (0.57) | ELANEGAAAKR1C3AKR1C1ACSL1 | |
| SCHEMBL10455506 | 0.78 | S1PR5 (0.40) | S1PR5ELANEAKR1C3AKR1C1PDE4A | |
| SCHEMBL10454524 | 0.75 | EPHX2 (0.44) | S1PR5ELANEGAAPDE4APDE4B | |
| SCHEMBL10454503 | 0.75 | OPRM1 (0.47) | S1PR5ELANEGAAAKR1C3AKR1C1 | |
| SCHEMBL26857799 | 0.73 | AKR1C3 (0.51) | AKR1C3AKR1C1ACSL1ACSL3ACSL6 | |
| SCHEMBL10455806 | 0.72 | ELANE (0.45) | ELANEGAAPOLBALDH1A1 | |
| SCHEMBL10454520 | 0.72 | ACSL1 (0.43) | ELANEACSL1PDE4APDE4DACSL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210772-B1 | 3-[(4-Aroyl)phenoxy(or phenylthio)]cyclopentanecarboxylic acid analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-06-06 | — | — | EP | claimed |
| EP-0210772-B1 | 3-[(4-Aroyl)phenoxy(or phenylthio)]cyclopentanecarboxylic acid analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-06-06 | — | — | EP | disclosed |
| US-4916147-A | 3-[(4-Aroyl) phenoxy (or phenylthio)]-cyclopentanecarboxylic acid analogues and treatment of cerebral edema therewith | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-04-10 | — | — | US | disclosed |