Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSL1 | P33121 | 4/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | ACSL3 | O95573 | 1/20 | 0.42 |
| ▸ | ACSL6 | Q9UKU0 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10454504 | 0.87 | ELANE (0.43) | ACSL1SRD5A2ACSL3ACSL6ELANE | |
| SCHEMBL10454520 | 0.86 | ACSL1 (0.43) | ACSL1SRD5A2ACSL3ACSL6ELANE | |
| SCHEMBL10455781 | 0.82 | ELANE (0.57) | ACSL1ACSL3ACSL6ELANEFFAR4 | |
| SCHEMBL10455487 | 0.79 | EPHX2 (0.39) | ELANEDGAT1SOAT1LSSEPHX2 | |
| SCHEMBL10455653 | 0.79 | ELANE (0.45) | ELANEFFAR4DGAT1ALDH1A1LMNA | |
| SCHEMBL10454525 | 0.78 | KMT2A (0.53) | ACSL1ACSL3ACSL6ELANEDGAT1 | |
| SCHEMBL10454503 | 0.77 | OPRM1 (0.47) | ELANEFFAR4DGAT1SOAT1MAPK1 | |
| SCHEMBL26857799 | 0.76 | AKR1C3 (0.51) | ACSL1ACSL3ACSL6FFAR4DGAT1 | |
| SCHEMBL10455456 | 0.76 | KMT2A (0.44) | ACSL1ACSL3ACSL6ELANEMAPK1 | |
| SCHEMBL10454523 | 0.75 | MAPT (0.54) | SRD5A2MAPK1HPGDHTTGRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210772-B1 | 3-[(4-Aroyl)phenoxy(or phenylthio)]cyclopentanecarboxylic acid analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-06-06 | — | — | EP | claimed |
| EP-0210772-A2 | 3-[(4-Aroyl)phenoxy(or phenylthio)]cyclopentanecarboxylic acid analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1987-02-04 | — | — | EP | claimed |
| EP-0210772-B1 | 3-[(4-Aroyl)phenoxy(or phenylthio)]cyclopentanecarboxylic acid analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-06-06 | — | — | EP | disclosed |
| US-4916147-A | 3-[(4-Aroyl) phenoxy (or phenylthio)]-cyclopentanecarboxylic acid analogues and treatment of cerebral edema therewith | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-04-10 | — | — | US | disclosed |