Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ELANE | P08246 | 2/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | ACSL1 | P33121 | 2/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ACSL3 | O95573 | 1/20 | 0.39 |
| ▸ | ACSL6 | Q9UKU0 | 1/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10455484 | 0.90 | KMT2A (0.42) | KMT2AELANEDGAT1EPHX2FAAH | |
| SCHEMBL10455517 | 0.90 | KMT2A (0.42) | KMT2AELANEDGAT1EPHX2FAAH | |
| SCHEMBL10454520 | 0.88 | ACSL1 (0.43) | KMT2AELANERAB9AACSL1KCNH2 | |
| SCHEMBL10455809 | 0.87 | EPHX2 (0.43) | ELANEDGAT1EPHX2FAAHACSL1 | |
| SCHEMBL10454523 | 0.87 | MAPT (0.54) | KMT2ARAB9AEPHX2FAAHPOLB | |
| SCHEMBL10455781 | 0.87 | ELANE (0.57) | ELANEDGAT1EPHX2FAAHACSL1 | |
| SCHEMBL10454504 | 0.86 | ELANE (0.43) | KMT2AELANEDGAT1EPHX2FAAH | |
| SCHEMBL10454526 | 0.82 | GRIK1 (0.47) | RAB9AEPHX2BTKKCNH2AKR1C3 | |
| SCHEMBL10455757 | 0.82 | ACSL1 (0.40) | KMT2AELANEDGAT1EPHX2FAAH | |
| SCHEMBL10455778 | 0.81 | RORC (0.38) | KMT2AELANEDGAT1EPHX2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210772-B1 | 3-[(4-Aroyl)phenoxy(or phenylthio)]cyclopentanecarboxylic acid analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-06-06 | — | — | EP | claimed |
| EP-0210772-A2 | 3-[(4-Aroyl)phenoxy(or phenylthio)]cyclopentanecarboxylic acid analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1987-02-04 | — | — | EP | claimed |
| EP-0210772-B1 | 3-[(4-Aroyl)phenoxy(or phenylthio)]cyclopentanecarboxylic acid analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-06-06 | — | — | EP | disclosed |
| US-4916147-A | 3-[(4-Aroyl) phenoxy (or phenylthio)]-cyclopentanecarboxylic acid analogues and treatment of cerebral edema therewith | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-04-10 | — | — | US | disclosed |
| EP-0210772-A2 | 3-[(4-Aroyl)phenoxy(or phenylthio)]cyclopentanecarboxylic acid analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1987-02-04 | — | — | EP | disclosed |