Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 2/20 | 0.44 |
| ▸ | RORC | P51449 | 7/20 | 0.43 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10454495 | 0.90 | RORC (0.40) | CCR3RORCACSL1GRIK1GRIA2 | |
| SCHEMBL10455483 | 0.90 | RORC (0.41) | RORCACSL1GRIK1GRIA2PDE4A | |
| SCHEMBL9765552 | 0.90 | RORC (0.41) | RORCACSL1GRIK1GRIA2PDE4A | |
| SCHEMBL10455473 | 0.89 | KMT2A (0.44) | RORCGRIK1GRIA2PDE4APDE4B | |
| SCHEMBL10454501 | 0.89 | RORC (0.44) | CCR3RORCACSL1GRIK1GRIA2 | |
| SCHEMBL10455486 | 0.89 | RORC (0.41) | CCR3RORCACSL1GRIK1GRIA2 | |
| SCHEMBL10454522 | 0.87 | ACSL1 (0.48) | RORCACSL1GRIK1GRIA2PDE4A | |
| SCHEMBL10455503 | 0.85 | POLB (0.40) | RORCALDH1A1 | |
| SCHEMBL10454493 | 0.83 | RORC (0.43) | RORCACSL1GRIK1GRIA2PDE4A | |
| SCHEMBL10455778 | 0.82 | RORC (0.38) | RORCACSL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210772-B1 | 3-[(4-Aroyl)phenoxy(or phenylthio)]cyclopentanecarboxylic acid analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-06-06 | — | — | EP | claimed |
| EP-0210772-A2 | 3-[(4-Aroyl)phenoxy(or phenylthio)]cyclopentanecarboxylic acid analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1987-02-04 | — | — | EP | claimed |
| EP-0210772-B1 | 3-[(4-Aroyl)phenoxy(or phenylthio)]cyclopentanecarboxylic acid analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-06-06 | — | — | EP | disclosed |
| US-4916147-A | 3-[(4-Aroyl) phenoxy (or phenylthio)]-cyclopentanecarboxylic acid analogues and treatment of cerebral edema therewith | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-04-10 | — | — | US | disclosed |
| EP-0210772-A2 | 3-[(4-Aroyl)phenoxy(or phenylthio)]cyclopentanecarboxylic acid analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1987-02-04 | — | — | EP | disclosed |