Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | FNTA | P49354 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 12/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 5/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 9/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7174967 | 0.84 | MEN1 (0.45) | MEN1KMT2AALDH1A1FNTAPKM | |
| SCHEMBL7706265 | 0.81 | MEN1 (0.50) | MEN1KMT2AALDH1A1FNTAPKM | |
| SCHEMBL13273469 | 0.72 | MEN1 (0.38) | MEN1KMT2AALDH1A1FNTAPKM | |
| SCHEMBL230169 | 0.71 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1FNTAPKM | |
| SCHEMBL20610531 | 0.71 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1FNTAPKM | |
| SCHEMBL19296597 | 0.71 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1FNTAPKM | |
| SCHEMBL17385233 | 0.70 | FNTA (0.53) | MEN1KMT2AALDH1A1FNTAPKM | |
| SCHEMBL10357402 | 0.70 | CYP3A4 (0.34) | — | |
| SCHEMBL19994535 | 0.69 | ALDH1A1 (0.39) | MEN1KMT2AALDH1A1FNTAPKM | |
| SCHEMBL30617255 | 0.69 | MCL1 (0.44) | MEN1KMT2AALDH1A1FNTAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4909854-A | Mixed with tricyclic ether | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1990-03-20 | — | — | US | disclosed |
| US-4782192-A | PERFUMES, FLAVORS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1988-11-01 | — | — | US | disclosed |
| US-RE32721-E | Bridged ketones and process for preparing same | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1988-07-26 | — | — | US | disclosed |
| US-4439354-A | Tricyclic alcohols, ethers and esters, process for preparing same and use thereof in augmenting or enhancing the organoleptic properites of consumable materials | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1984-03-27 | — | — | US | disclosed |
| US-4368128-A | Tricyclic alcohols, ethers and esters, process for preparing same and use thereof in augmenting or enhancing the organoleptic properties of consumable materials | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1983-01-11 | — | — | US | disclosed |
| US-4357360-A | Use of tricyclic alcohols, ethers and esters for augmenting or enhancing the aroma or taste of foodstuffs | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1982-11-02 | — | — | US | disclosed |
| US-4328109-A | 5,5-DIMETHYL-PERHYDRO-2,4A-METHANONAPHTHALENES | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1982-05-04 | — | — | US | disclosed |
| US-4293453-A | Process for using bridged ketones in augmenting or enhancing the organoleptic properties of consumable materials | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1981-10-06 | — | — | US | disclosed |
| US-4287081-A | SUCH AS DETERGENTS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1981-09-01 | — | — | US | disclosed |
| US-4285349-A | CIGARETTES | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1981-08-25 | — | — | US | disclosed |
| US-4250338-A | A 2,4A-METHANONAPHTHALENE-1(5H)-ONE BY CYCLIZATION OF A TETRAHYDRO-2-TETRALINCARBOXALDEHYDE USING A MINERAL ACID; PERFUMES; TOBACCO | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1981-02-10 | — | — | US | disclosed |