Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | FNTA | P49354 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 12/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 9/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10456239 | 0.81 | MEN1 (0.47) | MEN1KMT2AALDH1A1FNTAPKM | |
| SCHEMBL7179918 | 0.78 | MEN1 (0.50) | MEN1KMT2AALDH1A1FNTAPKM | |
| SCHEMBL623449 | 0.75 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL7173626 | 0.73 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL3840984 | 0.72 | MEN1 (0.41) | MEN1KMT2AALDH1A1FNTAPKM | |
| SCHEMBL13714694 | 0.72 | MEN1 (0.41) | MEN1KMT2AALDH1A1FNTAPKM | |
| SCHEMBL3840987 | 0.72 | MEN1 (0.41) | MEN1KMT2AALDH1A1FNTAPKM | |
| SCHEMBL10356894 | 0.72 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL17385233 | 0.70 | FNTA (0.53) | MEN1KMT2AALDH1A1FNTAPKM | |
| SCHEMBL7174967 | 0.70 | MEN1 (0.45) | MEN1KMT2AALDH1A1FNTAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002544245-A | — | — | 2002-12-24 | — | — | JP | claimed |
| EP-1178945-A1 | REACTIONS USING LEWIS ACIDS | QUEST INTERNATIONAL B.V. (NL) | 2002-02-13 | — | — | EP | claimed |
| WO-2000069777-A1 | REACTIONS USING LEWIS ACIDS | QUEST INTERNATIONAL B.V. (NL) | 2000-11-23 | — | — | WO | claimed |
| US-7678756-B2 | Substituted hydrogenated naphthalene derivatives and their use in fragrance formulations | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2010-03-16 | — | — | US | disclosed |
| US-7678756-B2 | Substituted hydrogenated naphthalene derivatives and their use in fragrance formulations | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2010-03-16 | — | — | US | disclosed |
| US-20090227685-A1 | SUBSTITUTED HYDROGENATED NAPHTHALENE DERIVATIVES AND THEIR USE IN FRAGRANCE FORMULATIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2009-09-10 | — | — | US | disclosed |
| US-20090227685-A1 | SUBSTITUTED HYDROGENATED NAPHTHALENE DERIVATIVES AND THEIR USE IN FRAGRANCE FORMULATIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2009-09-10 | — | — | US | disclosed |
| US-7375062-B1 | Substituted hydrogenated naphthalene derivatives and their use in fragrance formulations | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2008-05-20 | — | — | US | disclosed |
| US-7375062-B1 | Substituted hydrogenated naphthalene derivatives and their use in fragrance formulations | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2008-05-20 | — | — | US | disclosed |
| US-20080108544-A1 | SUBSTITUTED HYDROGENATED NAPHTHALENE DERIVATIVES AND THEIR USE IN FRAGRANCE FORMULATIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2008-05-08 | — | — | US | disclosed |
| US-20080108544-A1 | SUBSTITUTED HYDROGENATED NAPHTHALENE DERIVATIVES AND THEIR USE IN FRAGRANCE FORMULATIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2008-05-08 | — | — | US | disclosed |
| EP-1178945-A1 | REACTIONS USING LEWIS ACIDS | QUEST INTERNATIONAL B.V. (NL) | 2002-02-13 | — | — | EP | disclosed |
| WO-2000069777-A1 | REACTIONS USING LEWIS ACIDS | QUEST INTERNATIONAL B.V. (NL) | 2000-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108544-A1 | SUBSTITUTED HYDROGENATED NAPHTHALENE DERIVATIVES AND THEIR USE IN FRAGRANCE FORMULATIONS | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, H1-10, H1-0 | MEN1 2099/4885KMT2A 548/4885ALDH1A1 367/4885 |
| US-20090227685-A1 | SUBSTITUTED HYDROGENATED NAPHTHALENE DERIVATIVES AND THEIR USE IN FRAGRANCE FORMULATIONS | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HRH4, HRH1 | MEN1 2837/4885KMT2A 866/4885ALDH1A1 333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.