SCHEMBL10456331

SCHEMBL10456331

C=C(CC1(C)COCOC1)C(=O)OC

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
EPHX1 P07099 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4631285 0.93 EPHX1 (0.39) ALDH1A1EPHX1
SCHEMBL25251688 0.75
SCHEMBL631547 0.72 TSHR (0.36) ALDH1A1
SCHEMBL726325 0.72 EPHX1 (0.43) EPHX1
SCHEMBL21224218 0.70 ALDH1A1 (0.31) ALDH1A1
SCHEMBL1966339 0.70 EPHX1 (0.44) EPHX1
SCHEMBL21314217 0.69 ALDH1A1 (0.33) ALDH1A1
SCHEMBL28031398 0.69 EPHX1 (0.36) ALDH1A1EPHX1
SCHEMBL6912867 0.69 ALDH1A1 (0.42) ALDH1A1EPHX1
SCHEMBL10456516 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0154270-B1 HYDROPHILIC POLYMERS AND CONTACT LENSES MADE THEREFROM Pilkington Visioncare, Inc. (a Delaware corp.) (US) 1990-08-08 EP claimed
EP-0154270-A2 Hydrophilic polymers and contact lenses made therefrom Pilkington Visioncare, Inc. (a Delaware corp.) (US) 1985-09-11 EP claimed
EP-0154270-B1 HYDROPHILIC POLYMERS AND CONTACT LENSES MADE THEREFROM Pilkington Visioncare, Inc. (a Delaware corp.) (US) 1990-08-08 EP disclosed
EP-0154270-A2 Hydrophilic polymers and contact lenses made therefrom Pilkington Visioncare, Inc. (a Delaware corp.) (US) 1985-09-11 EP disclosed
US-4536554-A Hydrophilic polymers and contact lenses made therefrom BARNES-HIND, INC. (US) 1985-08-20 US disclosed