SCHEMBL10457136

SCHEMBL10457136

CC1(C)OB(c2ccc3c(-c4ccc(-c5ccc6ccccc6c5)cc4)c4ccccc4c(-c4ccc(-c5ccc6ccccc6c5)cc4)c3c2)OC1(C)C

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 9/20 0.72
LPL P06858 8/20 0.72
ESR1 P03372 2/20 0.36
ESR2 Q92731 2/20 0.36
PRMT5 O14744 1/20 0.36
WDR77 Q9BQA1 1/20 0.36
SNCA P37840 1/20 0.35
DGAT1 O75907 1/20 0.35
IRAK4 Q9NWZ3 1/20 0.35
CYP17A1 P05093 1/20 0.33
CYP19A1 P11511 1/20 0.33
CYP11B1 P15538 1/20 0.33
CYP11B2 P19099 1/20 0.33
CYP1A1 P04798 1/20 0.33
CYP1B1 Q16678 1/20 0.33
EGFR P00533 1/20 0.33
CHRNA1 P02708 1/20 0.33
CHRNG P07510 1/20 0.33
CHRNB1 P11230 1/20 0.33
CHRNB2 P17787 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1935027 0.95 LIPG (0.68) LIPGLPLPRMT5WDR77SNCA
SCHEMBL29980865 0.95 LIPG (0.68) LIPGLPLPRMT5WDR77SNCA
SCHEMBL12246537 0.94 LIPG (0.63) LIPGLPLESR1ESR2PRMT5
SCHEMBL10457213 0.93 LIPG (0.69) LIPGLPLPRMT5WDR77SNCA
SCHEMBL14506120 0.92 LIPG (0.68) LIPGLPLESR1ESR2PRMT5
SCHEMBL1007806 0.89 LIPG (0.76) LIPGLPLSNCADGAT1IRAK4
SCHEMBL13098741 0.89 LIPG (0.71) LIPGLPLSNCADGAT1IRAK4
SCHEMBL17268988 0.88 LIPG (0.74) LIPGLPLESR1ESR2PRMT5
SCHEMBL12626766 0.88 LIPG (0.66) LIPGLPLPRMT5WDR77DGAT1
SCHEMBL12578322 0.88 LIPG (0.61) LIPGLPLESR1ESR2SNCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1991514-B1 NOVEL ANTHRACENE DERIVATIVE AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEMICAL LTD (KR) 2017-12-20 EP disclosed
US-8222634-B2 Anthracene derivatives and organic electronic device using the same LG CHEM, LTD. (KR) 2012-07-17 US disclosed
US-8222634-B2 Anthracene derivatives and organic electronic device using the same LG CHEM, LTD. (KR) 2012-07-17 US disclosed
US-7965032-B2 Anthracene derivative and organic electronic device using the same LG CHEM, LTD. (KR) 2011-06-21 US disclosed
US-7965032-B2 Anthracene derivative and organic electronic device using the same LG CHEM, LTD. (KR) 2011-06-21 US disclosed
US-20110024725-A1 ANTHRACENE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEM, LTD. (KR) 2011-02-03 US disclosed
US-20110024725-A1 ANTHRACENE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEM, LTD. (KR) 2011-02-03 US disclosed
US-20070205412-A1 Novel anthracene derivative and organic electronic device using the same LG CHEM, LTD. (KR) 2007-09-06 US disclosed
US-20070205412-A1 Novel anthracene derivative and organic electronic device using the same LG CHEM, LTD. (KR) 2007-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110024725-A1 ANTHRACENE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING THE SAME VDAC2, VDAC3, ANXA1 LIPG 3587/4885LPL 4638/4885ESR1 23/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.