⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30274756 | 0.88 | ACHE (0.33) | — | |
| SCHEMBL30274755 | 0.88 | ACHE (0.33) | — | |
| SCHEMBL26882779 | 0.88 | ACHE (0.33) | — | |
| SCHEMBL27065057 | 0.88 | ACHE (0.33) | — | |
| SCHEMBL27056650 | 0.88 | ACHE (0.33) | — | |
| SCHEMBL24829627 | 0.87 | POLB (0.31) | — | |
| SCHEMBL13830602 | 0.86 | — | — | |
| SCHEMBL10459829 | 0.83 | TDP1 (0.31) | — | |
| SCHEMBL19981007 | 0.82 | P2RY6 (0.34) | — | |
| SCHEMBL1937265 | 0.82 | P2RY6 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180186826-A1 | PROTECTED MONOMER AND METHOD OF FINAL DEPROTECTION FOR RNA SYNTHESIS | AGILENT TECHNOLOGIES, INC. | 2018-07-05 | — | — | US | disclosed |
| US-9896472-B2 | Protected monomer and method of final deprotection for RNA synthesis | AGILENT TECHNOLOGIES, INC. (US) | 2018-02-20 | — | — | US | disclosed |
| US-20160002282-A1 | Protected Monomer and Method of Final Deprotection for RNA Synthesis | AGILENT TECHNOLOGIES, INC. | 2016-01-07 | — | — | US | disclosed |
| US-20120184724-A1 | PROTECTED MONOMERS AND METHODS OF DEPROTECTION FOR RNA SYNTHESIS | AGILENT TECHNOLOGIES, INC. (US) | 2012-07-19 | — | — | US | disclosed |