SCHEMBL13830602

CC(=O)Nc1ccn([C@@H]2O[C@@H]3CO[Si](C(C)C)(C(C)C)O[Si](C(C)C)(C(C)C)OC3[C@@H]2OC(=S)N2CCS(=O)(=O)CC2)c(=O)n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL10459480	0.88	—	—
SCHEMBL24829627	0.87	POLB (0.31)	—
SCHEMBL27065057	0.87	ACHE (0.33)	—
SCHEMBL27056650	0.87	ACHE (0.33)	—
SCHEMBL30274756	0.87	ACHE (0.33)	—
SCHEMBL30274755	0.87	ACHE (0.33)	—
SCHEMBL26882779	0.87	ACHE (0.33)	—
SCHEMBL10457924	0.86	—	—
SCHEMBL10457951	0.83	TDP1 (0.30)	—
SCHEMBL20346209	0.82	—	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20180186826-A1	PROTECTED MONOMER AND METHOD OF FINAL DEPROTECTION FOR RNA SYNTHESIS	AGILENT TECHNOLOGIES, INC.	2018-07-05	—	—	US	disclosed
US-9896472-B2	Protected monomer and method of final deprotection for RNA synthesis	AGILENT TECHNOLOGIES, INC. (US)	2018-02-20	—	—	US	disclosed
US-9273086-B2	Protected monomer and method of final deprotection for RNA synthesis	AGILENT TECHNOLOGIES, INC. (US)	2016-03-01	—	—	US	disclosed
US-20160002282-A1	Protected Monomer and Method of Final Deprotection for RNA Synthesis	AGILENT TECHNOLOGIES, INC.	2016-01-07	—	—	US	disclosed
US-20120289691-A1	PROTECTED MONOMER AND METHOD OF FINAL DEPROTECTION FOR RNA SYNTHESIS	AGILENT TECHNOLOGIES, INC. (US)	2012-11-15	—	—	US	disclosed