Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.39 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14228209 | 0.84 | ERN1 (0.49) | ERN1NPC1RAB9ARECQLMAPT | |
| SCHEMBL8760999 | 0.82 | ERN1 (0.47) | ERN1NPC1RAB9ARECQLMAPT | |
| SCHEMBL8581084 | 0.79 | ERN1 (0.50) | ERN1NPC1RAB9ARECQLMAPT | |
| SCHEMBL4585380 | 0.78 | NPC1 (0.53) | ERN1NPC1RAB9ARECQLSMN1; SMN2 | |
| SCHEMBL4164827 | 0.78 | ERN1 (0.53) | ERN1NPC1RAB9ARECQLMAPT | |
| SCHEMBL27295142 | 0.78 | ERN1 (0.49) | ERN1NPC1RAB9ARECQLMAPT | |
| SCHEMBL7811547 | 0.78 | HTR1A (0.49) | ERN1NPC1RAB9ARECQLMAPT | |
| SCHEMBL4164822 | 0.78 | ERN1 (0.53) | ERN1NPC1RAB9ARECQLMAPT | |
| SCHEMBL28340296 | 0.78 | ERN1 (0.49) | ERN1NPC1RAB9ARECQLMAPT | |
| SCHEMBL5816489 | 0.76 | ERN1 (0.57) | ERN1NPC1RAB9ARECQLMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4960884-A | Insecticides, nematocides, pesticides and miticides | FMC CORPORATION (US) | 1990-10-02 | — | — | US | disclosed |