Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27295142 | 0.86 | ERN1 (0.49) | ERN1ALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL10458181 | 0.78 | ERN1 (0.50) | ERN1ALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL8581084 | 0.78 | ERN1 (0.50) | ERN1ALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL4164822 | 0.77 | ERN1 (0.53) | ERN1ALDH1A1RAB9ANPC1RECQL | |
| SCHEMBL4164827 | 0.77 | ERN1 (0.53) | ERN1ALDH1A1RAB9ANPC1RECQL | |
| SCHEMBL14228209 | 0.77 | ERN1 (0.49) | ERN1ALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL7811547 | 0.77 | HTR1A (0.49) | ERN1ALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL4585380 | 0.77 | NPC1 (0.53) | ERN1RAB9ANPC1RECQLMEN1 | |
| SCHEMBL30720039 | 0.76 | ALDH1A1 (0.41) | ALDH1A1HPGDRAB9ANPC1RECQL | |
| SCHEMBL16345906 | 0.76 | ALDH1A1 (0.37) | ERN1ALDH1A1HPGDRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110642818-B | Method for preparing benzofuran-2-carboxamide compound | 云南师范大学 | 2023-05-30 | — | — | CN | claimed |
| CN-110642818-A | Method for preparing benzofuran-2-formamide compound | 云南师范大学 | 2020-01-03 | — | — | CN | claimed |
| CN-110642818-B | Method for preparing benzofuran-2-carboxamide compound | 云南师范大学 | 2023-05-30 | — | — | CN | disclosed |
| CN-110642818-A | Method for preparing benzofuran-2-formamide compound | 云南师范大学 | 2020-01-03 | — | — | CN | disclosed |