Ethylene

Ethylene

SCHEMBL10458293

C=C.Nc1ccc(C=O)cc1

nearest known ligand 0.48

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 1/20 0.48
CYP2A6 P11509 4/20 0.48
HSD17B10 Q99714 1/20 0.48
ALDH5A1 P51649 1/20 0.48
ABAT P80404 1/20 0.48
APP P05067 2/20 0.46
ALDH1A1 P00352 6/20 0.46
MEN1 O00255 1/20 0.44
MAPT P10636 1/20 0.44
KMT2A Q03164 1/20 0.44
CYP19A1 P11511 2/20 0.44
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
KDM4E B2RXH2 1/20 0.42
CYP2A13 Q16696 1/20 0.42
STS P08842 1/20 0.41
BRD4 O60885 1/20 0.39
ALDH3A1 P30838 1/20 0.39
ALDH1A3 P47895 1/20 0.39
CYP3A4 P08684 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28553043 0.94 CYP2A6 (0.52) TYRCYP2A6HSD17B10ALDH5A1ABAT
SCHEMBL214899 0.94
SCHEMBL28226740 0.94 CYP2A6 (0.52) TYRCYP2A6HSD17B10ALDH5A1ABAT
Hydrochloric Acid SCHEMBL28738883 0.92 CYP2A6 (0.50) TYRCYP2A6HSD17B10ALDH5A1ABAT
SCHEMBL27952608 0.92 CYP2A6 (0.50) TYRCYP2A6HSD17B10ALDH5A1ABAT
SCHEMBL28362581 0.92 CYP2A6 (0.50) TYRCYP2A6HSD17B10ALDH5A1ABAT
Ethylene Glycol SCHEMBL10480574 0.89 ALDH5A1 (0.44) TYRCYP2A6HSD17B10ALDH5A1ABAT
SCHEMBL13659420 0.86 ALDH1A1 (0.58) TYRCYP2A6HSD17B10ALDH5A1ABAT
SCHEMBL5415522 0.86 CYP19A1 (0.61) TYRCYP2A6HSD17B10ALDH5A1ABAT
SCHEMBL21908192 0.86 ALDH1A1 (0.58) TYRCYP2A6HSD17B10ALDH5A1ABAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4977272-A Radiation absorbers THE STANDARD OIL COMPANY (US) 1990-12-11 US disclosed