Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808263 | 0.86 | L3MBTL1 (0.68) | L3MBTL1MAPTMEN1PKMKMT2A | |
| SCHEMBL2936738 | 0.84 | KDM4E (0.61) | L3MBTL1MAPTTDP1KCNH2CYP1A2 | |
| SCHEMBL1032880 | 0.83 | KDM4E (0.68) | L3MBTL1MAPTMEN1PKMKMT2A | |
| SCHEMBL2094937 | 0.83 | MEN1 (0.58) | L3MBTL1MAPTMEN1PKMKMT2A | |
| SCHEMBL19337507 | 0.82 | L3MBTL1 (0.53) | L3MBTL1MAPTMEN1PKMKMT2A | |
| Hydrochloric Acid SCHEMBL6492504 | 0.81 | KDM4E (0.72) | L3MBTL1MAPTMEN1PKMKMT2A | |
| SCHEMBL1249120 | 0.81 | HTR1B (0.56) | L3MBTL1MAPTMEN1PKMKMT2A | |
| SCHEMBL3255231 | 0.81 | L3MBTL1 (0.56) | L3MBTL1MAPTMEN1PKMKMT2A | |
| SCHEMBL5660214 | 0.80 | L3MBTL1 (0.59) | L3MBTL1MAPTMEN1PKMKMT2A | |
| SCHEMBL5824396 | 0.80 | L3MBTL1 (0.56) | L3MBTL1MAPTMEN1PKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4960884-A | Insecticides, nematocides, pesticides and miticides | FMC CORPORATION (US) | 1990-10-02 | — | — | US | claimed |
| EP-2426125-B1 | 1,4 disubstituted 3 cyano pyridone derivatives and their use as positive allosteric modulators of mGluR2 receptors | JANSSEN PHARMACEUTICALS INC (US) | 2015-12-02 | — | — | EP | disclosed |