Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | HTR1B | P28222 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10457900 | 0.89 | L3MBTL1 (0.63) | KDM4ELMNAMAPTL3MBTL1TDP1 | |
| SCHEMBL22111020 | 0.85 | L3MBTL1 (0.60) | KDM4ELMNAMAPTL3MBTL1TDP1 | |
| SCHEMBL23582876 | 0.85 | HTR1A (0.57) | KDM4EMAPTL3MBTL1TDP1KCNH2 | |
| SCHEMBL29847096 | 0.85 | HTR1A (0.57) | KDM4EMAPTL3MBTL1TDP1KCNH2 | |
| SCHEMBL10456733 | 0.85 | KDM4E (0.47) | KDM4ELMNAMAPTJAK2GAA | |
| SCHEMBL10932879 | 0.84 | GAA (0.72) | KDM4ELMNAMAPTJAK2GAA | |
| SCHEMBL10458296 | 0.84 | L3MBTL1 (0.55) | LMNAMAPTGAAL3MBTL1TDP1 | |
| SCHEMBL15579434 | 0.84 | TDP1 (0.53) | KDM4ELMNAMAPTL3MBTL1TDP1 | |
| SCHEMBL1619632 | 0.84 | HTR7 (0.58) | KDM4ELMNAMAPTL3MBTL1CYP1A2 | |
| SCHEMBL10458218 | 0.84 | KDM4E (0.45) | KDM4ELMNAMAPTJAK2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104194800-B | Fluoric bis(diphenyl)acetylene nematic negative liquid crystal, synthetic method and application | FUJIAN SHAOWU YONGJING CHEMICAL CO., LTD. (CN) | 2016-03-09 | — | — | CN | claimed |
| CN-103333697-B | Nematic negative liquid crystal containing 2,3,5,6-tetrafluorotolane, synthetic method and application | FUJIAN SHAOWU YONGJING CHEMICAL CO LTD | 2015-06-03 | — | — | CN | claimed |
| CN-104194800-A | Fluorine-containing diphenyldiacetylene nematic negative liquid crystal, synthesis method and application | FUJIAN SHAOWU YONGJING CHEMICAL CO LTD | 2014-12-10 | — | — | CN | claimed |
| CN-103333697-A | Nematic negative liquid crystal containing 2,3,5,6-tetrafluorotolane, synthetic method and application | Shanghai tianwen chemical co ltd | 2013-10-02 | — | — | CN | claimed |
| US-4960884-A | Insecticides, nematocides, pesticides and miticides | FMC CORPORATION (US) | 1990-10-02 | — | — | US | claimed |
| CN-113999685-B | Liquid crystal compound containing dicyclohexyl, preparation method, composition and element | 西安近代化学研究所 | 2023-05-02 | — | — | CN | disclosed |
| CN-113999685-A | Liquid crystal compound containing bicyclohexene group, preparation method, composition and element | 西安近代化学研究所 | 2022-02-01 | — | — | CN | disclosed |
| CN-112759509-A | Compound, liquid crystal composition and display device | 阜阳欣奕华材料科技有限公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-110903832-B | Negative liquid crystal compound, liquid crystal composition containing negative liquid crystal compound and application of negative liquid crystal compound | 上海瓜呱科技有限公司 | 2021-02-12 | — | — | CN | disclosed |
| CN-110903832-A | Negative liquid crystal compound, liquid crystal composition containing negative liquid crystal compound and application of negative liquid crystal compound | 上海瓜呱科技有限公司 | 2020-03-24 | — | — | CN | disclosed |
| CN-104194800-B | Fluoric bis(diphenyl)acetylene nematic negative liquid crystal, synthetic method and application | FUJIAN SHAOWU YONGJING CHEMICAL CO., LTD. (CN) | 2016-03-09 | — | — | CN | disclosed |
| CN-103333697-B | Nematic negative liquid crystal containing 2,3,5,6-tetrafluorotolane, synthetic method and application | FUJIAN SHAOWU YONGJING CHEMICAL CO LTD | 2015-06-03 | — | — | CN | disclosed |
| EP-0916639-A1 | LIQUID CRYSTAL COMPOUNDS, LIQUID CRYSTAL COMPOSITIONS CONTAINING THE COMPOUNDS, AND LIQUID CRYSTAL DISPLAY DEVICES MADE BY USING THE COMPOSITIONS | CHISSO CORPORATION (JP) | 1999-05-19 | — | — | EP | disclosed |
| EP-0363458-B1 | 2,3-DIFLUOROBENZENES | MERCK PATENT GMBH (DE) | 1994-08-03 | — | — | EP | disclosed |
| EP-0308438-B1 | LIQUID CRYSTAL PHASE CONTAINING TOLANES | MERCK PATENT GmbH (DE) | 1993-09-29 | — | — | EP | disclosed |
| US-5087764-A | Deprotonation of a 1-substituted-2,3-difluorobenzene using an organometallic compound and reacting the reaction product with an electrophile | Merck Patent Gesellschaft mit beschrankter Hafung (DE) | 1992-02-11 | — | — | US | disclosed |
| EP-0363458-A1 | 2,3-DIFLUOROBENZENES. | MERCK PATENT GMBH (DE) | 1990-04-18 | — | — | EP | disclosed |
| WO-1989008629-A1 | PROCESS FOR PREPARING 2,3-DIFLUOROBENZENES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-09-21 | — | — | WO | disclosed |
| EP-0308438-A1 | Liquid crystal phase containing tolanes. | MERCK PATENT GMBH (DE) | 1989-03-29 | — | — | EP | disclosed |
| WO-1988007514-A1 | TOLANES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1988-10-06 | — | — | WO | disclosed |