Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21753692 | 0.84 | EPHX1 (0.52) | KMT2ARAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL10633483 | 0.83 | CA12 (0.57) | KMT2ARAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL10456813 | 0.81 | PPID (0.54) | KMT2ARAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL10458387 | 0.80 | CA12 (0.44) | KMT2ARAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL10458697 | 0.79 | MAPT (0.44) | KMT2ARAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL10458695 | 0.79 | MAPT (0.44) | KMT2ARAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL10458422 | 0.79 | NLRP3 (0.45) | KMT2ARAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL10458464 | 0.78 | POLB (0.50) | KMT2ARAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL10458661 | 0.78 | PPID (0.40) | KMT2ARAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL10457967 | 0.78 | MEN1 (0.49) | KMT2ARAB9AMAPTNPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4977272-A | Radiation absorbers | THE STANDARD OIL COMPANY (US) | 1990-12-11 | — | — | US | disclosed |
| US-4740611-A | N,N'-disubstituted ureas | THE STANDARD OIL COMPANY (US) | 1988-04-26 | — | — | US | disclosed |