Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | F7 | P08709 | 5/20 | 0.48 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | PPIA | P62937 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21753692 | 0.87 | EPHX1 (0.52) | POLBSMN1; SMN2RAB9AKMT2AMEN1 | |
| SCHEMBL10458695 | 0.82 | MAPT (0.44) | POLBF7F2SMN1; SMN2RAB9A | |
| SCHEMBL10458697 | 0.82 | MAPT (0.44) | POLBF7F2SMN1; SMN2RAB9A | |
| SCHEMBL10633474 | 0.81 | CA12 (0.65) | POLBF7F2SMN1; SMN2RAB9A | |
| SCHEMBL4631479 | 0.79 | ROCK2 (0.62) | POLBSMN1; SMN2 | |
| SCHEMBL1409910 | 0.78 | ALDH1A1 (0.66) | POLBSMN1; SMN2RAB9APARP10MAPT | |
| SCHEMBL10458465 | 0.78 | KMT2A (0.49) | POLBSMN1; SMN2RAB9AMAPTKMT2A | |
| SCHEMBL10458385 | 0.78 | CA12 (0.50) | POLBF7F2SMN1; SMN2RAB9A | |
| SCHEMBL10456811 | 0.78 | PPID (0.56) | SMN1; SMN2RAB9AL3MBTL1MAPTKMT2A | |
| SCHEMBL10458421 | 0.77 | CA12 (0.49) | POLBF7F2SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4977272-A | Radiation absorbers | THE STANDARD OIL COMPANY (US) | 1990-12-11 | — | — | US | disclosed |
| US-4740611-A | N,N'-disubstituted ureas | THE STANDARD OIL COMPANY (US) | 1988-04-26 | — | — | US | disclosed |