Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | USP5 | P45974 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10457062 | 0.96 | CYP2A6 (0.56) | CYP2A6MAPTHPGDALDH1A1NPC1 | |
| SCHEMBL11744077 | 0.86 | AKR1C3 (0.56) | CYP2A6MAPTHPGDALDH1A1CYP3A4 | |
| SCHEMBL29451111 | 0.85 | CYP2A6 (0.79) | CYP2A6MAPTHPGDALDH1A1NPC1 | |
| SCHEMBL599006 | 0.85 | CYP2A6 (0.79) | CYP2A6MAPTHPGDALDH1A1NPC1 | |
| SCHEMBL11736009 | 0.84 | CYP2A6 (0.53) | CYP2A6MAPTHPGDALDH1A1NPC1 | |
| SCHEMBL10458015 | 0.83 | KDM4E (0.52) | CYP2A6ALDH1A1KMT2AMEN1EIF4A3 | |
| SCHEMBL14790427 | 0.83 | UGT2B7 (0.58) | CYP2A6MAPTHPGDALDH1A1NPC1 | |
| SCHEMBL10365027 | 0.81 | CYP2A6 (0.49) | CYP2A6MAPTHPGDALDH1A1NPC1 | |
| SCHEMBL8081677 | 0.81 | KDM4E (0.55) | EIF4A3CYP2C9UGT2B7RXRARXRB | |
| SCHEMBL11459020 | 0.80 | AKR1C3 (0.62) | CYP2A6MAPTHPGDALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4935537-A | OXIDIZING ACYLALKYLNAPHTHALENE WITH PEROXIDE, OXIDIZING PRODUCT WITH OXYGEN USING CATALYST CONTAINING COBALT AND BROMINE COMPOUNDS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1990-06-19 | — | — | US | disclosed |
| US-4801737-A | Process for producing acyloxynaphthoic acids | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1989-01-31 | — | — | US | disclosed |
| EP-0170273-B1 | PROCESS FOR PRODUCING ACYLOXYNAPHTHOIC ACIDS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1988-12-28 | — | — | EP | disclosed |
| EP-0170273-A2 | Process for producing acyloxynaphthoic acids | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1986-02-05 | — | — | EP | disclosed |