SCHEMBL8081677

SCHEMBL8081677

CC(C)c1ccc2cc(C(=O)O)ccc2c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.55
RXRA P19793 2/20 0.53
RXRB P28702 2/20 0.53
RXRG P48443 1/20 0.53
RARA P10276 4/20 0.52
RARB P10826 4/20 0.52
RARG P13631 4/20 0.52
EIF4A3 P38919 1/20 0.51
GRIN2D O15399 1/20 0.51
GRIN2A Q12879 1/20 0.51
GRIN2B Q13224 1/20 0.51
GRIN2C Q14957 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.48
CSNK2A2 P19784 1/20 0.48
CSNK2B P67870 1/20 0.48
CSNK2A1 P68400 1/20 0.48
CSNK2A3 Q8NEV1 1/20 0.48
MRGPRX4 Q96LA9 1/20 0.48
CYP2C9 P11712 1/20 0.46
UGT2B7 P16662 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20178615 0.85 KDM4E (0.51) KDM4ERARARARBRARGGRIN2D
SCHEMBL11463895 0.85 AKR1C3 (0.63) KDM4ERARARARBRARGAKR1C3
SCHEMBL9622171 0.85 RARA (0.51) KDM4ERXRARXRBRXRGRARA
SCHEMBL19554193 0.85 KDM4E (0.50) KDM4ERARARARBRARGGRIN2D
SCHEMBL10457062 0.85 CYP2A6 (0.56) KDM4ERXRARXRBRXRGEIF4A3
SCHEMBL19774287 0.84 KDM4E (0.50) KDM4ERARARARBRARGGRIN2D
Acetic Acid SCHEMBL28429217 0.84 EIF4A3 (0.53) EIF4A3UGT2B7AKR1C3AKR1C2
Hydrogen Peroxide SCHEMBL9840257 0.83 UGT2B7 (0.60) EIF4A3UGT2B7AKR1C3AKR1C2
Hydrogen Peroxide SCHEMBL9172508 0.83 UGT2B7 (0.60) EIF4A3UGT2B7AKR1C3AKR1C2
SCHEMBL10458095 0.83 KDM4E (0.52) KDM4ERXRARXRBRXRGEIF4A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112441908-B Method for synthesizing 2,6-naphthalene dicarboxylic acid 中国石油化工股份有限公司 2023-04-07 CN claimed
CN-112441908-A Method for synthesizing 2,6-naphthalene dicarboxylic acid 中国石油化工股份有限公司 2021-03-05 CN claimed
US-4681978-A OXIDATION OF 2,6-DIISOPROPYLNAPHTHALENE USING A COBALT AND/OR MANGANESE SALT CATALYST KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1987-07-21 US claimed
US-4638087-A OXIDATION TO ALCOHOL OR PEROXIDE KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1987-01-20 US claimed
JP-61236750-A None JP disclosed
JP-61236747-A None JP disclosed
JP-8143510-A None JP disclosed
JP-61215353-A None JP disclosed
CN-114426480-B Hydrofining method of crude 2,6-naphthalene dicarboxylic acid 中国石油化工股份有限公司 2024-03-26 CN disclosed
CN-113754534-B Method for purifying crude2,6-naphthalene dicarboxylic acid 中国石油化工股份有限公司 2023-10-31 CN disclosed
CN-112441908-B Method for synthesizing 2,6-naphthalene dicarboxylic acid 中国石油化工股份有限公司 2023-04-07 CN disclosed
CN-112441909-B Method for synthesizing 2,6-naphthalene dicarboxylic acid 中国石油化工股份有限公司 2023-04-07 CN disclosed
US-4681978-A OXIDATION OF 2,6-DIISOPROPYLNAPHTHALENE USING A COBALT AND/OR MANGANESE SALT CATALYST KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1987-07-21 US disclosed
US-4681978-A OXIDATION OF 2,6-DIISOPROPYLNAPHTHALENE USING A COBALT AND/OR MANGANESE SALT CATALYST KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1987-07-21 US disclosed
US-4638087-A OXIDATION TO ALCOHOL OR PEROXIDE KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1987-01-20 US disclosed
US-4638087-A OXIDATION TO ALCOHOL OR PEROXIDE KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1987-01-20 US disclosed
JP-S61236747-A PRODUCTION OF 6-ISOPROPYL-2-NAPHTHOIC ACID TEIJIN YUKA KK 1986-10-22 JP disclosed
JP-S61236750-A PRODUCTION OF 6-HYDROXY-2-NAPHTHOIC ACID ESTER TEIJIN YUKA KK 1986-10-22 JP disclosed
JP-S61215353-A 2-SUBSTITUTED-NAPHTHALENE-6-CARBOXYLIC ACID AND PRODUCTION THEREOF KUREHA CHEM IND CO LTD 1986-09-25 JP disclosed
US-4607117-A FROM THE 2-ISOPROPYL COMPOUND USING COBALT OR MANGANESE CONTAINING CATALYST KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1986-08-19 US disclosed