Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.79 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | PRKCI | P41743 | 1/20 | 0.45 |
| ▸ | S100A4 | P26447 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL599006 | 1.00 | CYP2A6 (0.79) | CYP2A6MAPTHPGDALDH1A1RAB9A | |
| SCHEMBL15105728 | 0.92 | CYP2A6 (0.69) | CYP2A6MAPTHPGDALDH1A1RAB9A | |
| SCHEMBL21215857 | 0.92 | CYP2A6 (0.69) | CYP2A6MAPTHPGDALDH1A1RAB9A | |
| SCHEMBL834744 | 0.92 | CYP2A6 (0.68) | CYP2A6MAPTHPGDALDH1A1RAB9A | |
| SCHEMBL3558873 | 0.91 | CYP2A6 (0.68) | CYP2A6MAPTHPGDALDH1A1RAB9A | |
| SCHEMBL31402831 | 0.89 | CYP2A6 (0.66) | CYP2A6MAPTHPGDALDH1A1RAB9A | |
| SCHEMBL9719302 | 0.89 | CYP2A6 (1.00) | CYP2A6MAPTHPGDALDH1A1RAB9A | |
| SCHEMBL31402829 | 0.89 | CYP2A6 (0.66) | CYP2A6MAPTHPGDALDH1A1RAB9A | |
| SCHEMBL31402830 | 0.89 | CYP2A6 (0.66) | CYP2A6MAPTHPGDALDH1A1RAB9A | |
| SCHEMBL43058 | 0.88 | ALDH1A1 (0.71) | CYP2A6MAPTHPGDALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114144520-A | Enhanced nucleic acid polymerization by aromatic compounds | 斯特拉托斯基因公司 | 2022-03-04 | — | — | CN | disclosed |