SCHEMBL10458672

SCHEMBL10458672

CCCNc1cc2ccc(C)cc2o1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
KDM4E B2RXH2 2/20 0.38
MAPT P10636 1/20 0.38
TAS1R3 Q7RTX0 3/20 0.37
TAS1R1 Q7RTX1 3/20 0.37
APP P05067 1/20 0.36
CYP1A2 P05177 2/20 0.35
CYP2A6 P11509 2/20 0.35
MAOB P27338 4/20 0.35
PSMB8 P28062 1/20 0.35
KEAP1 Q14145 1/20 0.35
MAOA P21397 1/20 0.34
DRD2 P14416 1/20 0.33
DRD4 P21917 1/20 0.33
ELANE P08246 1/20 0.33
HSD17B10 Q99714 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9826190 0.88 ALDH1A1 (0.41) ALDH1A1KDM4EMAPTTAS1R3TAS1R1
Hydrochloric Acid SCHEMBL10460619 0.86 ALDH1A1 (0.40) ALDH1A1KDM4EMAPTTAS1R3TAS1R1
SCHEMBL9826049 0.81 MAOB (0.51) ALDH1A1KDM4EMAPTTAS1R3TAS1R1
SCHEMBL9826458 0.71 HDAC3 (0.52) ALDH1A1KDM4EMAPTTAS1R3TAS1R1
SCHEMBL13699027 0.71 ALDH1A1 (0.44) ALDH1A1KDM4EMAPTAPPCYP1A2
SCHEMBL10458671 0.70 ALDH1A1 (0.41) ALDH1A1KDM4EMAPTTAS1R3TAS1R1
SCHEMBL424398 0.70 HDAC3 (0.48) ALDH1A1KDM4EMAPTTAS1R3TAS1R1
SCHEMBL10460620 0.69 CA12 (0.43) ALDH1A1KDM4EMAPTTAS1R3TAS1R1
SCHEMBL9826946 0.69 APP (0.38) ALDH1A1MAPTAPPCYP2A6MAOB
SCHEMBL9827049 0.69 CYP1A2 (0.40) ALDH1A1KDM4EMAPTCYP1A2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4932998-A LOW PHYTOTOXICITY FOR PADDY RICE PLANTS IDEMITSU KOSAN COMPANY LIMITED (JP) 1990-06-12 US disclosed