Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9386142 | 0.69 | ALDH1A1 (0.32) | ALDH1A1SMN1; SMN2TDP1TSHR | |
| SCHEMBL17333129 | 0.69 | ALDH1A1 (0.32) | ALDH1A1SMN1; SMN2TDP1TSHR | |
| SCHEMBL17559511 | 0.68 | SMN1; SMN2 (0.43) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL3455337 | 0.68 | SMN1; SMN2 (0.43) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL93383 | 0.66 | — | — | |
| SCHEMBL177653 | 0.65 | — | — | |
| SCHEMBL3208036 | 0.65 | — | — | |
| SCHEMBL21795691 | 0.65 | SMN1; SMN2 (0.41) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL1889993 | 0.65 | — | — | |
| SCHEMBL28881398 | 0.65 | TSHR (0.42) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990009411-A2 | MODIFICATION OF ADDITION-CROSSLINKABLE SILICON ELASTOMERS WITH BLOCK COPOLYMERIZATES CONTAINING POLYSILOXANE SEGMENTS | WACKER-CHEMIE GMBH (DE) | 1990-08-23 | — | — | WO | disclosed |