Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.56 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28377838 | 0.96 | LMNA (0.52) | LMNACYP3A4CYP2D6MAPK3ASAH1 | |
| Ethyl Acetate SCHEMBL28885628 | 0.87 | LMNA (0.51) | LMNACYP3A4CYP2D6MAPK3ASAH1 | |
| SCHEMBL11741360 | 0.83 | LMNA (0.61) | LMNACYP3A4CYP2D6MAPK3ASAH1 | |
| Acetic Acid SCHEMBL28371708 | 0.82 | LMNA (0.54) | LMNACYP3A4CYP2D6MAPK3ASAH1 | |
| SCHEMBL11666682 | 0.80 | LMNA (0.61) | LMNACYP3A4CYP2D6MAPK3ASAH1 | |
| SCHEMBL10459087 | 0.79 | ASAH1 (0.72) | LMNACYP3A4CYP2D6MAPK3ASAH1 | |
| SCHEMBL11602434 | 0.78 | LMNA (0.56) | LMNACYP3A4CYP2D6MAPK3ASAH1 | |
| Acetic Acid SCHEMBL28371629 | 0.77 | LMNA (0.58) | LMNACYP3A4CYP2D6MAPK3ASAH1 | |
| SCHEMBL11265773 | 0.77 | LMNA (0.46) | LMNACYP3A4CYP2D6MAPK3ASAH1 | |
| SCHEMBL12113266 | 0.77 | GRIA1 (0.45) | LMNACYP3A4CYP2D6MAPK3ASAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4071519-A | 1-Carbamoyl-5-fluorouracil derivatives | MITSUI TOATSU CHEMICALS, INCORPORATED (JA) | 1978-01-31 | — | — | US | claimed |
| US-4914105-A | NONTOXIC, REDUCED SIDE EFFECTS | FUJII SETSURO (JP) | 1990-04-03 | — | — | US | disclosed |
| US-4071519-A | 1-Carbamoyl-5-fluorouracil derivatives | MITSUI TOATSU CHEMICALS, INCORPORATED (JA) | 1978-01-31 | — | — | US | disclosed |